Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages

Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages

IntroductionMacrophages play a crucial immunological role in maintaining pregnancy. Placental malaria infection may cause dysfunction in decidual macrophages which then culminates in the associated pregnancy complications. Here, we determined the influence of placental malaria on decidual macrophage...

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Bibliographic Details
Main Authors: Fred Owino, Caroline Kijogi, Omu Anzala, Edwin Walong, Obiero Jael, Steven G. Nyanjom, Agola Lelo Eric, Bernard N. Kanoi, Jesse Gitaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
placental malaria
macrophages
M1/M2 macrophage polarization
transcription factors
angiogenic factors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1497936/full
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