Natural compounds from medicinal plants against COVID-19
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the past time, several infections control methods have been developed. Nevertheless, all of them have certain limitations: uncertain...
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| Format: | Article |
| Language: | English |
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Open Exploration
2023-08-01
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| Series: | Exploration of Drug Science |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A100817/100817.pdf |
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| author | Anton Kolodnitsky Nikita Ionov Irina Gravel Vladimir Poroikov |
| author_facet | Anton Kolodnitsky Nikita Ionov Irina Gravel Vladimir Poroikov |
| author_sort | Anton Kolodnitsky |
| collection | DOAJ |
| description | The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the past time, several infections control methods have been developed. Nevertheless, all of them have certain limitations: uncertainty in duration, limited efficacy of vaccines, and lack of effective drugs for COVID-19 treatment. So, the issue of creating drugs for symptomatic and etiotropic therapy is still relevant. This review summarizes the current knowledge of using natural compounds as anti-SARS-CoV-2 agents by analysing the results of in vitro studies and completed clinical trials (CTs). Also, this work highlighted the most active molecules and discussed the possibility of using some compounds in clinical practice. |
| format | Article |
| id | doaj-art-97c9a3a1ef954fff8efc008516290797 |
| institution | Kabale University |
| issn | 2836-7677 |
| language | English |
| publishDate | 2023-08-01 |
| publisher | Open Exploration |
| record_format | Article |
| series | Exploration of Drug Science |
| spelling | doaj-art-97c9a3a1ef954fff8efc0085162907972025-02-08T03:49:04ZengOpen ExplorationExploration of Drug Science2836-76772023-08-011425327510.37349/eds.2023.00017Natural compounds from medicinal plants against COVID-19Anton Kolodnitsky0https://orcid.org/0000-0002-1148-2602Nikita Ionov1https://orcid.org/0000-0001-5396-2789Irina Gravel2https://orcid.org/0000-0002-3735-2291Vladimir Poroikov3https://orcid.org/0000-0001-7937-2621Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 119121 Moscow, Russia; Department of Pharmaceutical Natural Science, Institute of Pharmacy Named after A.P. Nelyubin, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, RussiaLaboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 119121 Moscow, RussiaDepartment of Pharmaceutical Natural Science, Institute of Pharmacy Named after A.P. Nelyubin, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, RussiaLaboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 119121 Moscow, RussiaThe severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the past time, several infections control methods have been developed. Nevertheless, all of them have certain limitations: uncertainty in duration, limited efficacy of vaccines, and lack of effective drugs for COVID-19 treatment. So, the issue of creating drugs for symptomatic and etiotropic therapy is still relevant. This review summarizes the current knowledge of using natural compounds as anti-SARS-CoV-2 agents by analysing the results of in vitro studies and completed clinical trials (CTs). Also, this work highlighted the most active molecules and discussed the possibility of using some compounds in clinical practice.https://www.explorationpub.com/uploads/Article/A100817/100817.pdfsars-cov-2covid-19medicinal plantsnatural productsin vitro studiesclinical trials |
| spellingShingle | Anton Kolodnitsky Nikita Ionov Irina Gravel Vladimir Poroikov Natural compounds from medicinal plants against COVID-19 Exploration of Drug Science sars-cov-2 covid-19 medicinal plants natural products in vitro studies clinical trials |
| title | Natural compounds from medicinal plants against COVID-19 |
| title_full | Natural compounds from medicinal plants against COVID-19 |
| title_fullStr | Natural compounds from medicinal plants against COVID-19 |
| title_full_unstemmed | Natural compounds from medicinal plants against COVID-19 |
| title_short | Natural compounds from medicinal plants against COVID-19 |
| title_sort | natural compounds from medicinal plants against covid 19 |
| topic | sars-cov-2 covid-19 medicinal plants natural products in vitro studies clinical trials |
| url | https://www.explorationpub.com/uploads/Article/A100817/100817.pdf |
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