Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis

Various lipid and biopolymer-based nanocarriers have been developed to encapsulate food ingredients. The selection of nanocarrier type, preparation techniques, and loading methods should consider the compatibility of nutrient properties, nanocarrier composition, and product requirements. This review...

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Main Authors: Ruihan Huang, Hongdong Song, Sen Li, Xiao Guan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Food Chemistry: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259015752401037X
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author Ruihan Huang
Hongdong Song
Sen Li
Xiao Guan
author_facet Ruihan Huang
Hongdong Song
Sen Li
Xiao Guan
author_sort Ruihan Huang
collection DOAJ
description Various lipid and biopolymer-based nanocarriers have been developed to encapsulate food ingredients. The selection of nanocarrier type, preparation techniques, and loading methods should consider the compatibility of nutrient properties, nanocarrier composition, and product requirements. This review focuses on the loading methods for hydrophilic and hydrophobic substances, along with a detailed exploration of nanocarrier categorization, composition, and preparation methods. Both lipid-based and biopolymer-based nanoparticles exhibit the capability to encapsulate hydrophilic or hydrophobic substances. Liposomes and nanoemulsions allow simultaneous encapsulation of hydrophilic and hydrophobic ingredients, while solid lipid nanoparticles and nanostructured lipid carriers are suited for hydrophobic ingredients. The three-dimensional network structure of nanogels can efficiently load hydrophilic substances, while the functional groups in polysaccharides improve the loading capacity of hydrophobic substances through intermolecular interactions. As for protein nanoparticles, the selection of proteins with solubility characteristics analogous to the bioactives is crucial to achieve high encapsulation efficiency.
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institution Kabale University
issn 2590-1575
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Food Chemistry: X
spelling doaj-art-9988fe5b429c4638ae70789705a9a99e2025-02-12T05:32:13ZengElsevierFood Chemistry: X2590-15752025-01-0125102149Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysisRuihan Huang0Hongdong Song1Sen Li2Xiao Guan3School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, ChinaSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, ChinaSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, ChinaSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, China; Corresponding author at: School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.Various lipid and biopolymer-based nanocarriers have been developed to encapsulate food ingredients. The selection of nanocarrier type, preparation techniques, and loading methods should consider the compatibility of nutrient properties, nanocarrier composition, and product requirements. This review focuses on the loading methods for hydrophilic and hydrophobic substances, along with a detailed exploration of nanocarrier categorization, composition, and preparation methods. Both lipid-based and biopolymer-based nanoparticles exhibit the capability to encapsulate hydrophilic or hydrophobic substances. Liposomes and nanoemulsions allow simultaneous encapsulation of hydrophilic and hydrophobic ingredients, while solid lipid nanoparticles and nanostructured lipid carriers are suited for hydrophobic ingredients. The three-dimensional network structure of nanogels can efficiently load hydrophilic substances, while the functional groups in polysaccharides improve the loading capacity of hydrophobic substances through intermolecular interactions. As for protein nanoparticles, the selection of proteins with solubility characteristics analogous to the bioactives is crucial to achieve high encapsulation efficiency.http://www.sciencedirect.com/science/article/pii/S259015752401037XNanocarrierBioactive ingredientsControlled releaseLipidProteinPolysaccharides
spellingShingle Ruihan Huang
Hongdong Song
Sen Li
Xiao Guan
Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
Food Chemistry: X
Nanocarrier
Bioactive ingredients
Controlled release
Lipid
Protein
Polysaccharides
title Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
title_full Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
title_fullStr Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
title_full_unstemmed Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
title_short Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
title_sort selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food grade materials a systematic review and analysis
topic Nanocarrier
Bioactive ingredients
Controlled release
Lipid
Protein
Polysaccharides
url http://www.sciencedirect.com/science/article/pii/S259015752401037X
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AT senli selectionstrategyforencapsulationofhydrophilicandhydrophobicingredientswithfoodgradematerialsasystematicreviewandanalysis
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