Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing

Abstract Much of the therapeutic potential of mesenchymal stromal cells (MSCs) is underpinned by their secretome which varies significantly with source, donor and microenvironmental cues. Understanding these differences is essential to define the mechanisms of MSC-based tissue repair and optimise ce...

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Bibliographic Details
Main Authors: Margeaux Hodgson-Garms, Matthew J. Moore, Mikaël M. Martino, Kilian Kelly, Jessica E. Frith
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-024-00382-y
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