Polymer and nanocomposite fillers as advanced materials in biomedical applications
Polymer nanocomposites exhibit advanced mechanical, catalytic, magnetic, and bioactive properties, making them invaluable in areas such as tissue engineering, where their tunable degradation and mechanical profiles contribute to successful tissue repair and regeneration. Despite significant progress...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Nano Trends |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666978125000169 |
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| author | Angeline Julius Suresh Malakondaiah Raghu Babu Pothireddy |
| author_facet | Angeline Julius Suresh Malakondaiah Raghu Babu Pothireddy |
| author_sort | Angeline Julius |
| collection | DOAJ |
| description | Polymer nanocomposites exhibit advanced mechanical, catalytic, magnetic, and bioactive properties, making them invaluable in areas such as tissue engineering, where their tunable degradation and mechanical profiles contribute to successful tissue repair and regeneration. Despite significant progress, challenges remain, particularly in achieving uniform nanofiller distribution and predicting functional outcomes. Furthermore, the clinical translation of these materials is limited by gaps in toxicity assessment, biodegradation evaluation, and comprehensive in vivo studies. The exploration of supramolecular polymer nanocomposites remains in its infancy but holds immense promise for advancing nanomedical therapies. This review underscores the need for focused research on biocompatibility, functional predictability, and the integration of polymer nanocomposites into clinical diagnostics and therapeutic applications to bridge current limitations and unlock their full potential in the field of biomedicine. |
| format | Article |
| id | doaj-art-9b4054edcccd42c29fe80f1a8de608a3 |
| institution | Kabale University |
| issn | 2666-9781 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Nano Trends |
| spelling | doaj-art-9b4054edcccd42c29fe80f1a8de608a32025-02-08T05:01:29ZengElsevierNano Trends2666-97812025-03-019100087Polymer and nanocomposite fillers as advanced materials in biomedical applicationsAngeline Julius0Suresh Malakondaiah1Raghu Babu Pothireddy2Centre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India; Corresponding author.Centre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, IndiaAcadicell Innovations International Pvt. Ltd., Crescent Innovation & Incubation Council, Vandalur, Chennai, Tamil Nadu, IndiaPolymer nanocomposites exhibit advanced mechanical, catalytic, magnetic, and bioactive properties, making them invaluable in areas such as tissue engineering, where their tunable degradation and mechanical profiles contribute to successful tissue repair and regeneration. Despite significant progress, challenges remain, particularly in achieving uniform nanofiller distribution and predicting functional outcomes. Furthermore, the clinical translation of these materials is limited by gaps in toxicity assessment, biodegradation evaluation, and comprehensive in vivo studies. The exploration of supramolecular polymer nanocomposites remains in its infancy but holds immense promise for advancing nanomedical therapies. This review underscores the need for focused research on biocompatibility, functional predictability, and the integration of polymer nanocomposites into clinical diagnostics and therapeutic applications to bridge current limitations and unlock their full potential in the field of biomedicine.http://www.sciencedirect.com/science/article/pii/S2666978125000169Advanced materialsTissue engineeringVersatile bio-scaffoldsPolymer nanocompositesBiomedical applications |
| spellingShingle | Angeline Julius Suresh Malakondaiah Raghu Babu Pothireddy Polymer and nanocomposite fillers as advanced materials in biomedical applications Nano Trends Advanced materials Tissue engineering Versatile bio-scaffolds Polymer nanocomposites Biomedical applications |
| title | Polymer and nanocomposite fillers as advanced materials in biomedical applications |
| title_full | Polymer and nanocomposite fillers as advanced materials in biomedical applications |
| title_fullStr | Polymer and nanocomposite fillers as advanced materials in biomedical applications |
| title_full_unstemmed | Polymer and nanocomposite fillers as advanced materials in biomedical applications |
| title_short | Polymer and nanocomposite fillers as advanced materials in biomedical applications |
| title_sort | polymer and nanocomposite fillers as advanced materials in biomedical applications |
| topic | Advanced materials Tissue engineering Versatile bio-scaffolds Polymer nanocomposites Biomedical applications |
| url | http://www.sciencedirect.com/science/article/pii/S2666978125000169 |
| work_keys_str_mv | AT angelinejulius polymerandnanocompositefillersasadvancedmaterialsinbiomedicalapplications AT sureshmalakondaiah polymerandnanocompositefillersasadvancedmaterialsinbiomedicalapplications AT raghubabupothireddy polymerandnanocompositefillersasadvancedmaterialsinbiomedicalapplications |