Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis
Background: The COVID-19 pandemic has underscored the impact of secondary fungal infections on patient outcomes. This single-center study explores asymptomatic fungal infections in COVID-19-positive and COVID-19-negative pneumonia cases, elucidating the intricate relationship between viral respirato...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_2033_23 |
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| _version_ | 1823858136174297088 |
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| author | Dheerendra Kumar Mishra Pramod Kushwaha Pooja Gangwar Ajeet Singh Umesh Pratap Singh |
| author_facet | Dheerendra Kumar Mishra Pramod Kushwaha Pooja Gangwar Ajeet Singh Umesh Pratap Singh |
| author_sort | Dheerendra Kumar Mishra |
| collection | DOAJ |
| description | Background:
The COVID-19 pandemic has underscored the impact of secondary fungal infections on patient outcomes. This single-center study explores asymptomatic fungal infections in COVID-19-positive and COVID-19-negative pneumonia cases, elucidating the intricate relationship between viral respiratory illnesses and fungal co-infections.
Methods:
Conducted at a single center, this cross-sectional study examines the prevalence, risk factors, and clinical implications of asymptomatic fungal infections in patients with COVID-19-positive and COVID-19-negative pneumonia. Various demographic, clinical, and laboratory parameters were analyzed.
Results:
Fungal infections were significantly more prevalent in COVID-19 positive pneumonia cases (60%) compared to COVID-19 negative pneumonia cases (36%), with a notable P value of 0.016309. Furthermore, COVID-19-positive patients exhibited distinct clinical characteristics, including increased use of remdesivir (94%), higher rates of invasive mechanical ventilation (36%), and a prolonged hospital stay (14.29 days).
Conclusion:
This study sheds light on the heightened vulnerability to asymptomatic fungal infections in COVID-19-positive pneumonia cases. Understanding these infections prevalence and their associated factors is crucial for comprehensive patient care and may influence treatment strategies, emphasizing the need for targeted interventions in viral respiratory illnesses. |
| format | Article |
| id | doaj-art-9d6ce6c4ec5146ac86d3edddda58cd2a |
| institution | Kabale University |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-9d6ce6c4ec5146ac86d3edddda58cd2a2025-02-11T13:57:30ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352025-01-0114140140510.4103/jfmpc.jfmpc_2033_23Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysisDheerendra Kumar MishraPramod KushwahaPooja GangwarAjeet SinghUmesh Pratap SinghBackground: The COVID-19 pandemic has underscored the impact of secondary fungal infections on patient outcomes. This single-center study explores asymptomatic fungal infections in COVID-19-positive and COVID-19-negative pneumonia cases, elucidating the intricate relationship between viral respiratory illnesses and fungal co-infections. Methods: Conducted at a single center, this cross-sectional study examines the prevalence, risk factors, and clinical implications of asymptomatic fungal infections in patients with COVID-19-positive and COVID-19-negative pneumonia. Various demographic, clinical, and laboratory parameters were analyzed. Results: Fungal infections were significantly more prevalent in COVID-19 positive pneumonia cases (60%) compared to COVID-19 negative pneumonia cases (36%), with a notable P value of 0.016309. Furthermore, COVID-19-positive patients exhibited distinct clinical characteristics, including increased use of remdesivir (94%), higher rates of invasive mechanical ventilation (36%), and a prolonged hospital stay (14.29 days). Conclusion: This study sheds light on the heightened vulnerability to asymptomatic fungal infections in COVID-19-positive pneumonia cases. Understanding these infections prevalence and their associated factors is crucial for comprehensive patient care and may influence treatment strategies, emphasizing the need for targeted interventions in viral respiratory illnesses.https://journals.lww.com/10.4103/jfmpc.jfmpc_2033_23covid-19fungal infectionshospitalized patientsicuimmunocompromisedpneumonia |
| spellingShingle | Dheerendra Kumar Mishra Pramod Kushwaha Pooja Gangwar Ajeet Singh Umesh Pratap Singh Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis Journal of Family Medicine and Primary Care covid-19 fungal infections hospitalized patients icu immunocompromised pneumonia |
| title | Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis |
| title_full | Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis |
| title_fullStr | Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis |
| title_full_unstemmed | Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis |
| title_short | Assessment of asymptomatic fungal infections in COVID-19 positive and COVID-19 negative pneumonia: A comprehensive epidemiological analysis |
| title_sort | assessment of asymptomatic fungal infections in covid 19 positive and covid 19 negative pneumonia a comprehensive epidemiological analysis |
| topic | covid-19 fungal infections hospitalized patients icu immunocompromised pneumonia |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_2033_23 |
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