Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study
Abstract We aimed to determine the prevalence and risk factors of epiretinal membrane in a population-based study of residents aged 50 years and older in Fujian Province, Southeast China. The Fujian Eye Study is a population-based cross-sectional eye study in Fujian province, Southeast China. Reside...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-88234-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823862502673350656 |
|---|---|
| author | Yang Li Xiaoxin Li Yonghua Hu Bin Wang Mingqin Zhang Qinrui Hu |
| author_facet | Yang Li Xiaoxin Li Yonghua Hu Bin Wang Mingqin Zhang Qinrui Hu |
| author_sort | Yang Li |
| collection | DOAJ |
| description | Abstract We aimed to determine the prevalence and risk factors of epiretinal membrane in a population-based study of residents aged 50 years and older in Fujian Province, Southeast China. The Fujian Eye Study is a population-based cross-sectional eye study in Fujian province, Southeast China. Residents aged 50 years and older were enrolled and did the questionnaire (educational background, income, blood type, disease history, medication history, smoking, drinking and tea consumption, et al.), physical and ophthalmological examinations with height, weight, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), refraction, intraocular pressure (IOP), slit lamp, nonmydriatic fundus photograph and spectralis optical coherence tomography (OCT) imaging. Nonmydriatic fundus photograph and Spectralis OCT were used to assess ERM according to a standardised protocol. A total of 8173 residents were included in this study. Among them, 8.42% (95% CI 0.0782–0.0902) had ERM in at least one eye. Multiple logistic regression showed the presence of ERM was only associated with urbanization and geographic location, but not with age, sex, refractive error, IOP, SBP, DBP, HR, BMI, hypertension, diabetic mellitus, hyperlipidemia, education, income, smoking, alcohol and tea consumption. ERM is common among Chinese with 8.42% in at least one eye. Urbanization and geographic location are the only associated factors for ERM in Fujian Eye Study. |
| format | Article |
| id | doaj-art-9fa05c2cd25d4f1ca23504de33c332e2 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-9fa05c2cd25d4f1ca23504de33c332e22025-02-09T12:31:03ZengNature PortfolioScientific Reports2045-23222025-02-011511710.1038/s41598-025-88234-7Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye StudyYang Li0Xiaoxin Li1Yonghua Hu2Bin Wang3Mingqin Zhang4Qinrui Hu5Eye Institute and Affiliated Xiamen Eye Center of Xiamen University, School of Medicine, Xiamen UniversityEye Institute and Affiliated Xiamen Eye Center of Xiamen University, School of Medicine, Xiamen UniversityDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science CentreEye Institute and Affiliated Xiamen Eye Center of Xiamen University, School of Medicine, Xiamen UniversityEye Institute and Affiliated Xiamen Eye Center of Xiamen University, School of Medicine, Xiamen UniversityEye Institute and Affiliated Xiamen Eye Center of Xiamen University, School of Medicine, Xiamen UniversityAbstract We aimed to determine the prevalence and risk factors of epiretinal membrane in a population-based study of residents aged 50 years and older in Fujian Province, Southeast China. The Fujian Eye Study is a population-based cross-sectional eye study in Fujian province, Southeast China. Residents aged 50 years and older were enrolled and did the questionnaire (educational background, income, blood type, disease history, medication history, smoking, drinking and tea consumption, et al.), physical and ophthalmological examinations with height, weight, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), refraction, intraocular pressure (IOP), slit lamp, nonmydriatic fundus photograph and spectralis optical coherence tomography (OCT) imaging. Nonmydriatic fundus photograph and Spectralis OCT were used to assess ERM according to a standardised protocol. A total of 8173 residents were included in this study. Among them, 8.42% (95% CI 0.0782–0.0902) had ERM in at least one eye. Multiple logistic regression showed the presence of ERM was only associated with urbanization and geographic location, but not with age, sex, refractive error, IOP, SBP, DBP, HR, BMI, hypertension, diabetic mellitus, hyperlipidemia, education, income, smoking, alcohol and tea consumption. ERM is common among Chinese with 8.42% in at least one eye. Urbanization and geographic location are the only associated factors for ERM in Fujian Eye Study.https://doi.org/10.1038/s41598-025-88234-7Cross-sectional eye studyEpiretinal membranePrevalenceRelated factorUrbanizationGeographic location |
| spellingShingle | Yang Li Xiaoxin Li Yonghua Hu Bin Wang Mingqin Zhang Qinrui Hu Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study Scientific Reports Cross-sectional eye study Epiretinal membrane Prevalence Related factor Urbanization Geographic location |
| title | Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study |
| title_full | Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study |
| title_fullStr | Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study |
| title_full_unstemmed | Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study |
| title_short | Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study |
| title_sort | prevalence and associated factors of epiretinal membrane using spectralis oct in fujian eye study |
| topic | Cross-sectional eye study Epiretinal membrane Prevalence Related factor Urbanization Geographic location |
| url | https://doi.org/10.1038/s41598-025-88234-7 |
| work_keys_str_mv | AT yangli prevalenceandassociatedfactorsofepiretinalmembraneusingspectralisoctinfujianeyestudy AT xiaoxinli prevalenceandassociatedfactorsofepiretinalmembraneusingspectralisoctinfujianeyestudy AT yonghuahu prevalenceandassociatedfactorsofepiretinalmembraneusingspectralisoctinfujianeyestudy AT binwang prevalenceandassociatedfactorsofepiretinalmembraneusingspectralisoctinfujianeyestudy AT mingqinzhang prevalenceandassociatedfactorsofepiretinalmembraneusingspectralisoctinfujianeyestudy AT qinruihu prevalenceandassociatedfactorsofepiretinalmembraneusingspectralisoctinfujianeyestudy |