Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plants
Background and Purpose: The Erica genus, part of the Ericaceae family, consists of diverse evergreen shrubs known for their vibrant floral displays and adaptation to nutrient-poor soils. Traditionally, these plants have been used for their pharmacological properties, including anti-inflammatory, ant...
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| Language: | English |
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Elsevier
2025-02-01
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| Series: | Phytomedicine Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667031324001714 |
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| author | Francis Adu-Amankwaah Hleziphi V. Mpundu Kudakwashe Nyambo Paula Strauss Kudzanai Ian Tapfuma Ndivhuwo Tshililo Motunrayo Victoria Badejo Lawrence Mabasa Vuyo Mavumengwana Lucinda Baatjies |
| author_facet | Francis Adu-Amankwaah Hleziphi V. Mpundu Kudakwashe Nyambo Paula Strauss Kudzanai Ian Tapfuma Ndivhuwo Tshililo Motunrayo Victoria Badejo Lawrence Mabasa Vuyo Mavumengwana Lucinda Baatjies |
| author_sort | Francis Adu-Amankwaah |
| collection | DOAJ |
| description | Background and Purpose: The Erica genus, part of the Ericaceae family, consists of diverse evergreen shrubs known for their vibrant floral displays and adaptation to nutrient-poor soils. Traditionally, these plants have been used for their pharmacological properties, including anti-inflammatory, antimicrobial and antioxidant effects. Despite their widespread ethnomedicinal use, a comprehensive review of the pharmacological potential of Erica species is still lacking. Study Design and Methods: This review presents an overview of the phytochemical, ethnomedicinal, pharmacological and toxicological properties of Erica species. A systematic literature search was conducted using online databases to identify primary studies on the Erica genus. Keywords such as “Erica,” “antioxidant,” “anti-inflammatory,” “toxicology,” “phytochemistry,” “anticancer,” “antidiabetic,” “antidiuretic,” “pharmacology,” “ethnomedicine” and “cytotoxicity” were employed. The search covered studies published from July 1980 to February 2023. All plant names were verified through ''The Plant List'' (http://www.theplantlist.org/) and PlantZAfrica (https://pza.sanbi.org/), while chemical structures were confirmed using ChemDraw Ultra and PubChem(https://pubchem.ncbi.nlm.nih.gov/). Over 60 bioactive compounds, including myricetin, rutin and luteolin, were identified, exhibiting anti-inflammatory, antioxidant, antimicrobial, antidiabetic and anticancer properties. Additionally, traditional uses of Erica plants by indigenous cultures in treating various ailments were documented, highlighting the importance of this genus in ethnomedicine. Conclusion: This review provides a comprehensive reference for researchers, offering insights into the therapeutic potential of Erica species and guiding future investigations into their pharmacological benefits. |
| format | Article |
| id | doaj-art-9fc95acf57f2477e96c1e8e4c8dcd645 |
| institution | Kabale University |
| issn | 2667-0313 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Phytomedicine Plus |
| spelling | doaj-art-9fc95acf57f2477e96c1e8e4c8dcd6452025-02-10T04:35:10ZengElsevierPhytomedicine Plus2667-03132025-02-0151100697Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plantsFrancis Adu-Amankwaah0Hleziphi V. Mpundu1Kudakwashe Nyambo2Paula Strauss3Kudzanai Ian Tapfuma4Ndivhuwo Tshililo5Motunrayo Victoria Badejo6Lawrence Mabasa7Vuyo Mavumengwana8Lucinda Baatjies9DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownGrootbos Private Nature Reserve (GPNR), Grootbos, Western Cape, South AfricaDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownBiomedical Research and Innovation Platform (BRIP), Medical Research Council, Tygerberg, Cape Town, South AfricaDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town; Corresponding author.Background and Purpose: The Erica genus, part of the Ericaceae family, consists of diverse evergreen shrubs known for their vibrant floral displays and adaptation to nutrient-poor soils. Traditionally, these plants have been used for their pharmacological properties, including anti-inflammatory, antimicrobial and antioxidant effects. Despite their widespread ethnomedicinal use, a comprehensive review of the pharmacological potential of Erica species is still lacking. Study Design and Methods: This review presents an overview of the phytochemical, ethnomedicinal, pharmacological and toxicological properties of Erica species. A systematic literature search was conducted using online databases to identify primary studies on the Erica genus. Keywords such as “Erica,” “antioxidant,” “anti-inflammatory,” “toxicology,” “phytochemistry,” “anticancer,” “antidiabetic,” “antidiuretic,” “pharmacology,” “ethnomedicine” and “cytotoxicity” were employed. The search covered studies published from July 1980 to February 2023. All plant names were verified through ''The Plant List'' (http://www.theplantlist.org/) and PlantZAfrica (https://pza.sanbi.org/), while chemical structures were confirmed using ChemDraw Ultra and PubChem(https://pubchem.ncbi.nlm.nih.gov/). Over 60 bioactive compounds, including myricetin, rutin and luteolin, were identified, exhibiting anti-inflammatory, antioxidant, antimicrobial, antidiabetic and anticancer properties. Additionally, traditional uses of Erica plants by indigenous cultures in treating various ailments were documented, highlighting the importance of this genus in ethnomedicine. Conclusion: This review provides a comprehensive reference for researchers, offering insights into the therapeutic potential of Erica species and guiding future investigations into their pharmacological benefits.http://www.sciencedirect.com/science/article/pii/S2667031324001714CytotoxicityEricaEthnomedicineFynbosPharmacologyToxicology |
| spellingShingle | Francis Adu-Amankwaah Hleziphi V. Mpundu Kudakwashe Nyambo Paula Strauss Kudzanai Ian Tapfuma Ndivhuwo Tshililo Motunrayo Victoria Badejo Lawrence Mabasa Vuyo Mavumengwana Lucinda Baatjies Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plants Phytomedicine Plus Cytotoxicity Erica Ethnomedicine Fynbos Pharmacology Toxicology |
| title | Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plants |
| title_full | Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plants |
| title_fullStr | Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plants |
| title_full_unstemmed | Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plants |
| title_short | Phytochemical and pharmacological review of Erica Genus (L.) Ericaceae plants |
| title_sort | phytochemical and pharmacological review of erica genus l ericaceae plants |
| topic | Cytotoxicity Erica Ethnomedicine Fynbos Pharmacology Toxicology |
| url | http://www.sciencedirect.com/science/article/pii/S2667031324001714 |
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