Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study
Abstract Background Unhealthy diets contribute to the onset and progression of chronic kidney disease (CKD), with poor dietary habits identified as significant lifestyle factors that elevate CKD risk. Methods Data from the UK Biobank cohort, which included over 500,000 participants aged 40–69 from d...
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BMC
2025-02-01
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| Online Access: | https://doi.org/10.1186/s12889-025-21652-4 |
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| author | Yong-Ping Lu Bin Xia Xiao-Hua Wang Qiang-Sheng He Chang-Bo Qu Ying-Ying Xie Tian-Jiao Cui Si-Qing Wu Jin-Yu Zhao Zhi-Hua Zheng Ting Zhu Jin-Qiu Yuan Chun Tang |
| author_facet | Yong-Ping Lu Bin Xia Xiao-Hua Wang Qiang-Sheng He Chang-Bo Qu Ying-Ying Xie Tian-Jiao Cui Si-Qing Wu Jin-Yu Zhao Zhi-Hua Zheng Ting Zhu Jin-Qiu Yuan Chun Tang |
| author_sort | Yong-Ping Lu |
| collection | DOAJ |
| description | Abstract Background Unhealthy diets contribute to the onset and progression of chronic kidney disease (CKD), with poor dietary habits identified as significant lifestyle factors that elevate CKD risk. Methods Data from the UK Biobank cohort, which included over 500,000 participants aged 40–69 from diverse regions of England, Wales, and Scotland, were analyzed. Participants, who completed at least one online 24-hour dietary recall assessment, were included in the study. The baseline for analysis was the first 24-hour dietary recall in 2011, with follow-up extending until the earliest occurrence of CKD diagnosis, death, or the end of the study period. Results A total of 207,268 British individuals who completed at least one online 24-hour dietary recall assessment were included in this study. Four healthy dietary pattern scores were evaluated: the Healthy Plant-based Diet Index (hPDI), the Healthy Eating Index (HEI)-2015, the Mediterranean Diet (MED) Score, and the Alternative Mediterranean Diet (AMED) Score. These scores assessed the association between dietary patterns and the incidence of CKD. Relative to the lowest dietary scores, the HR for CKD was 0.79 (95% CI, 0.73–0.87) for the hPDI, 0.80 (95% CI, 0.73–0.87) for the HEI-2015, 0.86 (95% CI, 0.81–0.93) for the MED, and 0.84 (95% CI, 0.78–0.90) for the AMED (all p < 0.001). Conclusion This study provides robust evidence linking healthy dietary patterns to a reduced risk of CKD. Further clinical trials are needed to confirm whether adherence to such diets can lower the risk of CKD. |
| format | Article |
| id | doaj-art-a06b35df07344acfa62e947cc28bf322 |
| institution | Kabale University |
| issn | 1471-2458 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj-art-a06b35df07344acfa62e947cc28bf3222025-02-09T12:58:44ZengBMCBMC Public Health1471-24582025-02-0125111010.1186/s12889-025-21652-4Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort studyYong-Ping Lu0Bin Xia1Xiao-Hua Wang2Qiang-Sheng He3Chang-Bo Qu4Ying-Ying Xie5Tian-Jiao Cui6Si-Qing Wu7Jin-Yu Zhao8Zhi-Hua Zheng9Ting Zhu10Jin-Qiu Yuan11Chun Tang12Department of Nephrology, Center of Kidney and Urology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityClinical Big Data Research Center, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Nephrology, Center of Kidney and Urology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityClinical Big Data Research Center, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Traditional Chinese Medicine, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Nephrology, Center of Kidney and Urology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Nephrology, Center of Kidney and Urology, The Seventh Affiliated Hospital of Sun Yat-sen UniversitySchool of Medicine, Shenzhen Campus of Sun Yat-sen UniversityThe First Clinical Medical School, Lanzhou UniversityDepartment of Nephrology, Center of Kidney and Urology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Nephrology, Center of Kidney and Urology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityClinical Big Data Research Center, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Nephrology, Center of Kidney and Urology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityAbstract Background Unhealthy diets contribute to the onset and progression of chronic kidney disease (CKD), with poor dietary habits identified as significant lifestyle factors that elevate CKD risk. Methods Data from the UK Biobank cohort, which included over 500,000 participants aged 40–69 from diverse regions of England, Wales, and Scotland, were analyzed. Participants, who completed at least one online 24-hour dietary recall assessment, were included in the study. The baseline for analysis was the first 24-hour dietary recall in 2011, with follow-up extending until the earliest occurrence of CKD diagnosis, death, or the end of the study period. Results A total of 207,268 British individuals who completed at least one online 24-hour dietary recall assessment were included in this study. Four healthy dietary pattern scores were evaluated: the Healthy Plant-based Diet Index (hPDI), the Healthy Eating Index (HEI)-2015, the Mediterranean Diet (MED) Score, and the Alternative Mediterranean Diet (AMED) Score. These scores assessed the association between dietary patterns and the incidence of CKD. Relative to the lowest dietary scores, the HR for CKD was 0.79 (95% CI, 0.73–0.87) for the hPDI, 0.80 (95% CI, 0.73–0.87) for the HEI-2015, 0.86 (95% CI, 0.81–0.93) for the MED, and 0.84 (95% CI, 0.78–0.90) for the AMED (all p < 0.001). Conclusion This study provides robust evidence linking healthy dietary patterns to a reduced risk of CKD. Further clinical trials are needed to confirm whether adherence to such diets can lower the risk of CKD.https://doi.org/10.1186/s12889-025-21652-4Chronic kidney diseaseDietary patternDietary scoreIncidence |
| spellingShingle | Yong-Ping Lu Bin Xia Xiao-Hua Wang Qiang-Sheng He Chang-Bo Qu Ying-Ying Xie Tian-Jiao Cui Si-Qing Wu Jin-Yu Zhao Zhi-Hua Zheng Ting Zhu Jin-Qiu Yuan Chun Tang Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study BMC Public Health Chronic kidney disease Dietary pattern Dietary score Incidence |
| title | Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study |
| title_full | Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study |
| title_fullStr | Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study |
| title_full_unstemmed | Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study |
| title_short | Healthy dietary patterns and the incidence of chronic kidney disease: results from a prospective cohort study |
| title_sort | healthy dietary patterns and the incidence of chronic kidney disease results from a prospective cohort study |
| topic | Chronic kidney disease Dietary pattern Dietary score Incidence |
| url | https://doi.org/10.1186/s12889-025-21652-4 |
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