Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment
Objectives To assess the feasibility of delivering and evaluating a lifestyle programme for patients with colorectal cancer undergoing potentially curative treatments.Study design Non-randomised feasibility trial.Setting National Health Service (NHS) Tayside.Participants Adults with stage I–III colo...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2018-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/8/6/e021117.full |
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| author | Annie S Anderson Ronan E O’Carroll Martine Stead Robert J C Steele Mary Wells Maureen Macleod Anna Campbell Jacqui A Sugden Jackie Rodger Jennifer McKell |
| author_facet | Annie S Anderson Ronan E O’Carroll Martine Stead Robert J C Steele Mary Wells Maureen Macleod Anna Campbell Jacqui A Sugden Jackie Rodger Jennifer McKell |
| author_sort | Annie S Anderson |
| collection | DOAJ |
| description | Objectives To assess the feasibility of delivering and evaluating a lifestyle programme for patients with colorectal cancer undergoing potentially curative treatments.Study design Non-randomised feasibility trial.Setting National Health Service (NHS) Tayside.Participants Adults with stage I–III colorectal cancer.Intervention The programme targeted smoking, alcohol, physical activity, diet and weight management. It was delivered in three face-to-face counselling sessions (plus nine phone calls) by lifestyle coaches over three phases (1: presurgery, 2: surgical recovery and 3: post-treatment recovery).Primary outcome Feasibility measures (recruitment, retention, programme implementation, achieved measures, fidelity, factors affecting protocol adherence and acceptability).Secondary outcomes Measured changes in body weight, waist circumference, walking and self-reported physical activity, diet, smoking, alcohol intake, fatigue, bowel function and quality of life.Results Of 84 patients diagnosed, 22 (26%) were recruited and 15 (18%) completed the study. Median time for intervention delivery was 5.5 hours. Coaches reported covering most (>70%) of the intervention components but had difficulties during phase 2. Evaluation measures (except walk test) were achieved by all participants at baseline, and most (<90%) at end of phase 2 and phase 3, but <20% at end of phase 1. Protocol challenges included limited time between diagnosis and surgery and the presence of comorbidities. The intervention was rated highly by participants but limited support from NHS staff was noted. The majority of participants (77%) had a body mass index>25 kg/m2 and none was underweight. Physical activity data showed a positive trend towards increased activity overall, but no other changes in secondary outcomes were detected.Conclusions To make this intervention feasible for testing as a full trial, further research is required on (a) recruitment optimisation, (b) appropriate assessment tools, (c) protocols for phase 2 and 3, which can build in flexibility and (d) ways for NHS staff to facilitate the programme.Trial registration number ISRCTN52345929; Post-results. |
| format | Article |
| id | doaj-art-a130ff09089e435f84fdc1ddfdc2d523 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-a130ff09089e435f84fdc1ddfdc2d5232025-02-12T00:10:14ZengBMJ Publishing GroupBMJ Open2044-60552018-06-018610.1136/bmjopen-2017-021117Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatmentAnnie S Anderson0Ronan E O’Carroll1Martine Stead2Robert J C Steele3Mary Wells4Maureen Macleod5Anna Campbell6Jacqui A Sugden7Jackie Rodger8Jennifer McKell9Centre for Research into Cancer Prevention and Screening, Cancer Division, Medical Research Institute, Ninewells Medical School, Dundee, UK2 Division of Psychology, School of Natural Sciences, University of Stirling, Stirling, UK3 Institute for Social Marketing, Faculty of Health Sciences and Sport, University of Stirling, Stirling, UKCentre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UK5 Imperial College Healthcare NHS Trust, London, UK1 Division of Cancer Research, Centre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UKSport Exercise and Health, Edinburgh Napier University, Edinburgh, UK1 Division of Cancer Research, Centre for Research into Cancer Prevention and Screening, University of Dundee, Dundee, UKcolorectal specialist nurse5 Institute for Social Marketing, University of Stirling and the Open University, Stirling, UKObjectives To assess the feasibility of delivering and evaluating a lifestyle programme for patients with colorectal cancer undergoing potentially curative treatments.Study design Non-randomised feasibility trial.Setting National Health Service (NHS) Tayside.Participants Adults with stage I–III colorectal cancer.Intervention The programme targeted smoking, alcohol, physical activity, diet and weight management. It was delivered in three face-to-face counselling sessions (plus nine phone calls) by lifestyle coaches over three phases (1: presurgery, 2: surgical recovery and 3: post-treatment recovery).Primary outcome Feasibility measures (recruitment, retention, programme implementation, achieved measures, fidelity, factors affecting protocol adherence and acceptability).Secondary outcomes Measured changes in body weight, waist circumference, walking and self-reported physical activity, diet, smoking, alcohol intake, fatigue, bowel function and quality of life.Results Of 84 patients diagnosed, 22 (26%) were recruited and 15 (18%) completed the study. Median time for intervention delivery was 5.5 hours. Coaches reported covering most (>70%) of the intervention components but had difficulties during phase 2. Evaluation measures (except walk test) were achieved by all participants at baseline, and most (<90%) at end of phase 2 and phase 3, but <20% at end of phase 1. Protocol challenges included limited time between diagnosis and surgery and the presence of comorbidities. The intervention was rated highly by participants but limited support from NHS staff was noted. The majority of participants (77%) had a body mass index>25 kg/m2 and none was underweight. Physical activity data showed a positive trend towards increased activity overall, but no other changes in secondary outcomes were detected.Conclusions To make this intervention feasible for testing as a full trial, further research is required on (a) recruitment optimisation, (b) appropriate assessment tools, (c) protocols for phase 2 and 3, which can build in flexibility and (d) ways for NHS staff to facilitate the programme.Trial registration number ISRCTN52345929; Post-results.https://bmjopen.bmj.com/content/8/6/e021117.full |
| spellingShingle | Annie S Anderson Ronan E O’Carroll Martine Stead Robert J C Steele Mary Wells Maureen Macleod Anna Campbell Jacqui A Sugden Jackie Rodger Jennifer McKell Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment BMJ Open |
| title | Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment |
| title_full | Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment |
| title_fullStr | Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment |
| title_full_unstemmed | Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment |
| title_short | Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment |
| title_sort | feasibility study to assess the delivery of a lifestyle intervention treatwell for patients with colorectal cancer undergoing potentially curative treatment |
| url | https://bmjopen.bmj.com/content/8/6/e021117.full |
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