Characterisation of internal tremors and vibration symptoms
Objectives To describe the experiences of patients who have postacute sequelae SARS-CoV-2 infection with internal vibrations and tremors as a prominent component, we leveraged the efforts by Survivor Corps, a grassroots COVID-19 patient advocacy group, to gather information from individuals belongin...
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| Format: | Article |
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BMJ Publishing Group
2023-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/12/e077389.full |
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| author | Harlan M Krumholz Mitsuaki Sawano Richa Sharma Tianna Zhou Dorothy Massey Anna D Baker Diana Berrent Güthe Nick Güthe Suzanne Pincus Shidlovsky Liza Fisher Connor B Grady Cesar Caraballo |
| author_facet | Harlan M Krumholz Mitsuaki Sawano Richa Sharma Tianna Zhou Dorothy Massey Anna D Baker Diana Berrent Güthe Nick Güthe Suzanne Pincus Shidlovsky Liza Fisher Connor B Grady Cesar Caraballo |
| author_sort | Harlan M Krumholz |
| collection | DOAJ |
| description | Objectives To describe the experiences of patients who have postacute sequelae SARS-CoV-2 infection with internal vibrations and tremors as a prominent component, we leveraged the efforts by Survivor Corps, a grassroots COVID-19 patient advocacy group, to gather information from individuals belonging to its Facebook group with a history of COVID-19 suffering from vibrations and tremors.Setting and design A narrative analysis was performed on 140 emails and 450 social media comments from 140 individuals collected as a response to a call to >180 000 individuals participating in Survivor Corps between 15 July and 27 July 2021. We used common coding techniques and the constant comparative method for qualitative data synthesis and categorising emails. Coded data were entered into NVivo V.12 to identify recurrent themes, theme connections and supporting quotations. Comments were analysed using Word Clouds, generated with R V.4.0.3 using quanteda, wordcloud and tm packages.Main outcome measures Patient-reported long COVID symptom themes and domains related to internal tremors and vibration.Results The respondents’ emails represented 22 themes and 7 domains pertaining to their experience with internal tremor and vibrations. These domains were as follows: (1) symptom experience, description and anatomic location; (2) initial symptom onset; (3) symptom timing; (4) symptom triggers or alleviators; (5) change from baseline health status; (6) experience with medical establishment and (7) impact on individuals’ lives and livelihood. There were 22 themes in total, each corresponding to one of the broader domains. Among the responses, many described symptoms that varied in location, timing and triggers, occurred soon after their COVID-19 infection, and were markedly debilitating. There were often frustrating experiences with the healthcare system.Conclusions This study describes key themes and experiences among a group of people reporting long COVID and having a prolonged and debilitating symptom complex that prominently features internal tremors and vibrations. |
| format | Article |
| id | doaj-art-a1698f81d6c34c5087e74fb2442208e0 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-a1698f81d6c34c5087e74fb2442208e02025-02-12T02:30:10ZengBMJ Publishing GroupBMJ Open2044-60552023-12-01131210.1136/bmjopen-2023-077389Characterisation of internal tremors and vibration symptomsHarlan M Krumholz0Mitsuaki Sawano1Richa Sharma2Tianna Zhou3Dorothy Massey4Anna D Baker5Diana Berrent Güthe6Nick Güthe7Suzanne Pincus Shidlovsky8Liza Fisher9Connor B Grady10Cesar Caraballo11Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut, USACenter for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA1Department of PSM, Mahatma Gandhi Medical College, Jaipur Rajasthan, IndiaYale School of Medicine, New Haven, Connecticut, USACenter for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USASection of Stroke and Vascular Neurology, Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USASurvivor Corps, Washington, DC, Washington, USASurvivor Corps, Washington, DC, Washington, USASurvivor Corps, Washington, DC, Washington, USASurvivor Corps, Washington, DC, Washington, USADepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USACenter for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USAObjectives To describe the experiences of patients who have postacute sequelae SARS-CoV-2 infection with internal vibrations and tremors as a prominent component, we leveraged the efforts by Survivor Corps, a grassroots COVID-19 patient advocacy group, to gather information from individuals belonging to its Facebook group with a history of COVID-19 suffering from vibrations and tremors.Setting and design A narrative analysis was performed on 140 emails and 450 social media comments from 140 individuals collected as a response to a call to >180 000 individuals participating in Survivor Corps between 15 July and 27 July 2021. We used common coding techniques and the constant comparative method for qualitative data synthesis and categorising emails. Coded data were entered into NVivo V.12 to identify recurrent themes, theme connections and supporting quotations. Comments were analysed using Word Clouds, generated with R V.4.0.3 using quanteda, wordcloud and tm packages.Main outcome measures Patient-reported long COVID symptom themes and domains related to internal tremors and vibration.Results The respondents’ emails represented 22 themes and 7 domains pertaining to their experience with internal tremor and vibrations. These domains were as follows: (1) symptom experience, description and anatomic location; (2) initial symptom onset; (3) symptom timing; (4) symptom triggers or alleviators; (5) change from baseline health status; (6) experience with medical establishment and (7) impact on individuals’ lives and livelihood. There were 22 themes in total, each corresponding to one of the broader domains. Among the responses, many described symptoms that varied in location, timing and triggers, occurred soon after their COVID-19 infection, and were markedly debilitating. There were often frustrating experiences with the healthcare system.Conclusions This study describes key themes and experiences among a group of people reporting long COVID and having a prolonged and debilitating symptom complex that prominently features internal tremors and vibrations.https://bmjopen.bmj.com/content/13/12/e077389.full |
| spellingShingle | Harlan M Krumholz Mitsuaki Sawano Richa Sharma Tianna Zhou Dorothy Massey Anna D Baker Diana Berrent Güthe Nick Güthe Suzanne Pincus Shidlovsky Liza Fisher Connor B Grady Cesar Caraballo Characterisation of internal tremors and vibration symptoms BMJ Open |
| title | Characterisation of internal tremors and vibration symptoms |
| title_full | Characterisation of internal tremors and vibration symptoms |
| title_fullStr | Characterisation of internal tremors and vibration symptoms |
| title_full_unstemmed | Characterisation of internal tremors and vibration symptoms |
| title_short | Characterisation of internal tremors and vibration symptoms |
| title_sort | characterisation of internal tremors and vibration symptoms |
| url | https://bmjopen.bmj.com/content/13/12/e077389.full |
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