Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models
IntroductionConstitutive Photomorphogenesis Protein 1 homolog (COP1) is a conserved E3 ligase with key roles in several biological systems. Prior work in hepatocyte-derived tumors categorized COP1 as an oncogene, but its role in untransformed hepatocytes remains largely unexplored. Here, we have inv...
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Main Authors: | Sébastien Soubeyrand, Paulina Lau, Ruth McPherson |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-02-01
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Series: | Frontiers in Molecular Biosciences |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2025.1548582/full |
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