A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report
Contrast medium is frequently associated with allergic reactions and kidney dysfunction. However, contrast media can induce hemolytic anemia with a broad spectrum of hemolytic manifestations. We report a 38-year-old patient with very severe immune hemolytic anemia after the application of iomeprol d...
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| Format: | Article |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1464014/full |
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| author | Sabine Hermann Karina Althaus Migdat Mustafi Beate Mayer Peter Rosenberger Helene Anna Haeberle Alice Bernard |
| author_facet | Sabine Hermann Karina Althaus Migdat Mustafi Beate Mayer Peter Rosenberger Helene Anna Haeberle Alice Bernard |
| author_sort | Sabine Hermann |
| collection | DOAJ |
| description | Contrast medium is frequently associated with allergic reactions and kidney dysfunction. However, contrast media can induce hemolytic anemia with a broad spectrum of hemolytic manifestations. We report a 38-year-old patient with very severe immune hemolytic anemia after the application of iomeprol due to a CT of the thorax/abdomen. In this case report, we illustrate the diagnostics and treatment of life-threatening hemolytic anemia induced by a contrast medium that was successfully treated with eculizumab. |
| format | Article |
| id | doaj-art-a3be422b92af49d6bc2ad92cc759c19d |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-a3be422b92af49d6bc2ad92cc759c19d2025-02-11T06:59:46ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-02-011610.3389/fimmu.2025.14640141464014A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case reportSabine Hermann0Karina Althaus1Migdat Mustafi2Beate Mayer3Peter Rosenberger4Helene Anna Haeberle5Alice Bernard6Department of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, GermanyClinical and Experimental Transfusion Medicine, University Hospital Tuebingen, Tuebingen, GermanyDepartment of Thoracic and Vascular Surgery, University Hospital Saarland, Saarbruecken, GermanyInsitutition of Transfusion Medicine, Charité, Berlin, GermanyDepartment of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, GermanyDepartment of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, GermanyDepartment of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, GermanyContrast medium is frequently associated with allergic reactions and kidney dysfunction. However, contrast media can induce hemolytic anemia with a broad spectrum of hemolytic manifestations. We report a 38-year-old patient with very severe immune hemolytic anemia after the application of iomeprol due to a CT of the thorax/abdomen. In this case report, we illustrate the diagnostics and treatment of life-threatening hemolytic anemia induced by a contrast medium that was successfully treated with eculizumab.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1464014/fulldrug-induced hemolysiscontrast medium-induced hemolysiseculizumabhemolytic anemiaimmunological hemolysis |
| spellingShingle | Sabine Hermann Karina Althaus Migdat Mustafi Beate Mayer Peter Rosenberger Helene Anna Haeberle Alice Bernard A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report Frontiers in Immunology drug-induced hemolysis contrast medium-induced hemolysis eculizumab hemolytic anemia immunological hemolysis |
| title | A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report |
| title_full | A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report |
| title_fullStr | A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report |
| title_full_unstemmed | A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report |
| title_short | A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report |
| title_sort | hyper acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab a case report |
| topic | drug-induced hemolysis contrast medium-induced hemolysis eculizumab hemolytic anemia immunological hemolysis |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1464014/full |
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