Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function

The specific role of lysophosphatidic acid 2 (LPA2) in deep vein thrombosis (DVT) remains unclear.

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Main Authors: Bai Ruifeng, Yue Xinyang, Tian Xuan, Zhao Huiru, Liu Ying, Li Tian, Wu Jun
Format: Article
Language:English
Published: De Gruyter 2025-02-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2024-1137
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author Bai Ruifeng
Yue Xinyang
Tian Xuan
Zhao Huiru
Liu Ying
Li Tian
Wu Jun
author_facet Bai Ruifeng
Yue Xinyang
Tian Xuan
Zhao Huiru
Liu Ying
Li Tian
Wu Jun
author_sort Bai Ruifeng
collection DOAJ
description The specific role of lysophosphatidic acid 2 (LPA2) in deep vein thrombosis (DVT) remains unclear.
format Article
id doaj-art-aa310d435e994bffbb0a63a061b37e40
institution Kabale University
issn 2391-5463
language English
publishDate 2025-02-01
publisher De Gruyter
record_format Article
series Open Medicine
spelling doaj-art-aa310d435e994bffbb0a63a061b37e402025-02-10T13:24:40ZengDe GruyterOpen Medicine2391-54632025-02-01201351910.1515/med-2024-1137Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier functionBai Ruifeng0Yue Xinyang1Tian Xuan2Zhao Huiru3Liu Ying4Li Tian5Wu Jun6Department of Clinical Laboratory, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, ChinaDepartment of Clinical Laboratory, Peking University Fourth School of Clinical Medicine, Beijing, 100035, ChinaDepartment of Vascular Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, ChinaDepartment of Clinical Laboratory, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, ChinaBlood Transfusion Department, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, ChinaTianjin Key Laboratory of Acute Abdomen Disease-Associated Organ Injury and ITCWM Repair, Institute of Integrative Medicine of Acute Abdominal Diseases, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin300100, ChinaDepartment of Clinical Laboratory, Beijing Jishuitan Hospital, Capital Medical University, 31 Xinjiekou East St., Beijing, 100035, ChinaThe specific role of lysophosphatidic acid 2 (LPA2) in deep vein thrombosis (DVT) remains unclear.https://doi.org/10.1515/med-2024-1137deep vein thrombosislysophosphatidic acid 2vascular endothelial permeabilityendothelial cellszonula occludens-1
spellingShingle Bai Ruifeng
Yue Xinyang
Tian Xuan
Zhao Huiru
Liu Ying
Li Tian
Wu Jun
Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function
Open Medicine
deep vein thrombosis
lysophosphatidic acid 2
vascular endothelial permeability
endothelial cells
zonula occludens-1
title Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function
title_full Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function
title_fullStr Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function
title_full_unstemmed Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function
title_short Lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function
title_sort lysophosphatidic acid 2 alleviates deep vein thrombosis via protective endothelial barrier function
topic deep vein thrombosis
lysophosphatidic acid 2
vascular endothelial permeability
endothelial cells
zonula occludens-1
url https://doi.org/10.1515/med-2024-1137
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AT yuexinyang lysophosphatidicacid2alleviatesdeepveinthrombosisviaprotectiveendothelialbarrierfunction
AT tianxuan lysophosphatidicacid2alleviatesdeepveinthrombosisviaprotectiveendothelialbarrierfunction
AT zhaohuiru lysophosphatidicacid2alleviatesdeepveinthrombosisviaprotectiveendothelialbarrierfunction
AT liuying lysophosphatidicacid2alleviatesdeepveinthrombosisviaprotectiveendothelialbarrierfunction
AT litian lysophosphatidicacid2alleviatesdeepveinthrombosisviaprotectiveendothelialbarrierfunction
AT wujun lysophosphatidicacid2alleviatesdeepveinthrombosisviaprotectiveendothelialbarrierfunction