PHYSICOCHEMICAL PROPERTIES AND PHARMACOLOGY OFAMLODIPINE BESYLATE A BRIEF REVIEW
Hypertension is one of the well-studied risk factors for cardiovascular diseases and the oldest class of hypertensive drugsisthe calcium channel blockers.Amlodipine besylate (ADB) belongsto the dihydropyridine family and is known as an effective initial treatment for hypertension and angina. It has...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Baqai University Press
2024-10-01
|
| Series: | Baqai Journal of Health Sciences |
| Online Access: | https://journals.baqai.edu.pk/index.php/CS/article/view/108 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Hypertension is one of the well-studied risk factors for cardiovascular diseases and the oldest class of
hypertensive drugsisthe calcium channel blockers.Amlodipine besylate (ADB) belongsto the dihydropyridine
family and is known as an effective initial treatment for hypertension and angina. It has a gradual onset
of action and is administered in concomitant diseases with minimal side effects. Its basic mechanism of
action is the blockage of calcium ions influx into cardiac muscles and vascular muscles. The physical
appearance of ADB is white crystalline with a molecular weight of 567.1. Its 6.9 mg is equivalent to 5 mg
of amlodipine (AM) free base. This review focuses on all the basic aspects of ADB which is one of the
initial treatment regimens for cardiovascular diseases since last two decades
|
|---|---|
| ISSN: | 2312-4423 2312-6884 |