Safety profile of sacituzumab govitecan in patients with breast cancer: A systematic review and meta-analysis

Safety profile of sacituzumab govitecan in patients with breast cancer: A systematic review and meta-analysis

Background: Sacituzumab Govitecan (SG), a first-in-class anti-trophoblast cell surface antigen-2-directed antibody-drug conjugate (ADC), has shown clinically meaningful improvement in outcomes of patients with breast cancer (BC). However, it has also been accompanied by significant toxicity. Thus, w...

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Bibliographic Details
Main Authors: Maria Inez Dacoregio, Isabella Michelon, Caio Ernesto do Rego Castro, Francisco Cezar Aquino de Moraes, Guilherme Rossato de Almeida, Lis Victória Ravani, Maysa Vilbert, Ricardo Lima Barros Costa
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Breast
Subjects:
Sacituzumab govitecan
Antibody-drug conjugates
TROP-2
IMMU-132
Breast cancer
Safety
Online Access:http://www.sciencedirect.com/science/article/pii/S096097762400184X
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