Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience

OBJECTIVES: Neural tube defects, defined as the developmental malformations of the central nervous system, are seen in our country at a rate of three per thousand on average. Our study aims to retrospectively evaluate patients with neural tube defects hospitalized in our intensive care unit for the...

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Main Authors: Umit Ayse Tandircioglu, Cansu Kethuda Ensert Cihan, Hasan Tolga Celik, Burcak Bilginer, Sule Yigit
Format: Article
Language:English
Published: Medical Network 2022-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
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Online Access:https://gorm.com.tr/index.php/GORM/article/view/1314
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author Umit Ayse Tandircioglu
Cansu Kethuda Ensert Cihan
Hasan Tolga Celik
Burcak Bilginer
Sule Yigit
author_facet Umit Ayse Tandircioglu
Cansu Kethuda Ensert Cihan
Hasan Tolga Celik
Burcak Bilginer
Sule Yigit
author_sort Umit Ayse Tandircioglu
collection DOAJ
description OBJECTIVES: Neural tube defects, defined as the developmental malformations of the central nervous system, are seen in our country at a rate of three per thousand on average. Our study aims to retrospectively evaluate patients with neural tube defects hospitalized in our intensive care unit for the last decade. STUDY DESIGN: Demographic data, prenatal-maternal characteristics, surgical operation time, intensive care follow-up, and long-term neurological-developmental results of these patients were also evaluated. RESULTS: Eighty-six percent (n=31) of the patients were diagnosed prenatally. Arnold Chiari type 2 and type 3 malformation was 64% (n=23) and 3% (n=1), respectively. Eighty-nine (n=32) percent of these patients had meningomyelocele, whereas 90% (n=27) of them had defects in the lumbosacral region. The patients were operated on the median postnatal 9th day (4-27). Compared patients who were operated on in the 1st week to the patients operated on following the first week, any difference was not detected in terms of neuromotor and cognitive development, and urinary/stool incontinence frequency. Of 28 patients whose long-term follow-up was questioned, 7 (25%), 25 (89%), and 16 (57%) were able to walk, talk, and go to school along with being compatible with their peers, respectively. CONCLUSION: We presented our center's experience to make a significant contribution to the decrease of the neural tube defect frequency, which is commonly seen in our country compared to developed countries.
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institution Kabale University
issn 1300-4751
2602-4918
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publishDate 2022-12-01
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series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-ab22560995544070b75fcc94256a70a62025-02-11T21:16:14ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182022-12-0128310.21613/GORM.2022.1314Follow-Up of Newborns with Neural Tube Defects: A Single Center ExperienceUmit Ayse Tandircioglu0Cansu Kethuda Ensert Cihan1Hasan Tolga Celik2Burcak Bilginer3Sule Yigit4Hacettepe UniversityHacettepe UniversityHacettepe UniversityHacettepe UniversityHacettepe University OBJECTIVES: Neural tube defects, defined as the developmental malformations of the central nervous system, are seen in our country at a rate of three per thousand on average. Our study aims to retrospectively evaluate patients with neural tube defects hospitalized in our intensive care unit for the last decade. STUDY DESIGN: Demographic data, prenatal-maternal characteristics, surgical operation time, intensive care follow-up, and long-term neurological-developmental results of these patients were also evaluated. RESULTS: Eighty-six percent (n=31) of the patients were diagnosed prenatally. Arnold Chiari type 2 and type 3 malformation was 64% (n=23) and 3% (n=1), respectively. Eighty-nine (n=32) percent of these patients had meningomyelocele, whereas 90% (n=27) of them had defects in the lumbosacral region. The patients were operated on the median postnatal 9th day (4-27). Compared patients who were operated on in the 1st week to the patients operated on following the first week, any difference was not detected in terms of neuromotor and cognitive development, and urinary/stool incontinence frequency. Of 28 patients whose long-term follow-up was questioned, 7 (25%), 25 (89%), and 16 (57%) were able to walk, talk, and go to school along with being compatible with their peers, respectively. CONCLUSION: We presented our center's experience to make a significant contribution to the decrease of the neural tube defect frequency, which is commonly seen in our country compared to developed countries. https://gorm.com.tr/index.php/GORM/article/view/1314Long-term outcomesMeningomyeloceleNeural tube defectsNewborn
spellingShingle Umit Ayse Tandircioglu
Cansu Kethuda Ensert Cihan
Hasan Tolga Celik
Burcak Bilginer
Sule Yigit
Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience
Gynecology Obstetrics & Reproductive Medicine
Long-term outcomes
Meningomyelocele
Neural tube defects
Newborn
title Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience
title_full Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience
title_fullStr Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience
title_full_unstemmed Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience
title_short Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience
title_sort follow up of newborns with neural tube defects a single center experience
topic Long-term outcomes
Meningomyelocele
Neural tube defects
Newborn
url https://gorm.com.tr/index.php/GORM/article/view/1314
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AT hasantolgacelik followupofnewbornswithneuraltubedefectsasinglecenterexperience
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