Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review
Prolactinoma is the most common pituitary tumor, with clinical presentations varying according to sex, age of onset, tumor size, and prolactin (PRL) levels. These tumors are rare in the pediatric and adolescent populations. Hyperprolactinemia leads to hypogonadotropic hypogonadism, resulting in repr...
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Format: | Article |
Language: | English |
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Wiley
2025-01-01
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Series: | Case Reports in Endocrinology |
Online Access: | http://dx.doi.org/10.1155/crie/5388529 |
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author | Sánchez M. Otazú M. Furtenbach P. Piñeyro M. |
author_facet | Sánchez M. Otazú M. Furtenbach P. Piñeyro M. |
author_sort | Sánchez M. |
collection | DOAJ |
description | Prolactinoma is the most common pituitary tumor, with clinical presentations varying according to sex, age of onset, tumor size, and prolactin (PRL) levels. These tumors are rare in the pediatric and adolescent populations. Hyperprolactinemia leads to hypogonadotropic hypogonadism, resulting in reproductive, metabolic, sexual, and skeletal consequences that can affect puberty development. Here, we present the case of a 23-year-old male patient diagnosed with arrested puberty secondary to a macroprolactinoma. The clinical presentation, diagnostic approach, therapeutic management, and a literature review are discussed. |
format | Article |
id | doaj-art-ac255f319c964138ac8854e6c73e9083 |
institution | Kabale University |
issn | 2090-651X |
language | English |
publishDate | 2025-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Endocrinology |
spelling | doaj-art-ac255f319c964138ac8854e6c73e90832025-02-08T00:00:05ZengWileyCase Reports in Endocrinology2090-651X2025-01-01202510.1155/crie/5388529Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature ReviewSánchez M.0Otazú M.1Furtenbach P.2Piñeyro M.3Unidad Académica de Endocrinología y MetabolismoUnidad Académica de Endocrinología y MetabolismoUnidad Académica de Endocrinología y MetabolismoUnidad Académica de Endocrinología y MetabolismoProlactinoma is the most common pituitary tumor, with clinical presentations varying according to sex, age of onset, tumor size, and prolactin (PRL) levels. These tumors are rare in the pediatric and adolescent populations. Hyperprolactinemia leads to hypogonadotropic hypogonadism, resulting in reproductive, metabolic, sexual, and skeletal consequences that can affect puberty development. Here, we present the case of a 23-year-old male patient diagnosed with arrested puberty secondary to a macroprolactinoma. The clinical presentation, diagnostic approach, therapeutic management, and a literature review are discussed.http://dx.doi.org/10.1155/crie/5388529 |
spellingShingle | Sánchez M. Otazú M. Furtenbach P. Piñeyro M. Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review Case Reports in Endocrinology |
title | Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review |
title_full | Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review |
title_fullStr | Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review |
title_full_unstemmed | Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review |
title_short | Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review |
title_sort | arrested puberty in a young adult with a macroprolactinoma case report and literature review |
url | http://dx.doi.org/10.1155/crie/5388529 |
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