Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review

Prolactinoma is the most common pituitary tumor, with clinical presentations varying according to sex, age of onset, tumor size, and prolactin (PRL) levels. These tumors are rare in the pediatric and adolescent populations. Hyperprolactinemia leads to hypogonadotropic hypogonadism, resulting in repr...

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Main Authors: Sánchez M., Otazú M., Furtenbach P., Piñeyro M.
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/crie/5388529
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author Sánchez M.
Otazú M.
Furtenbach P.
Piñeyro M.
author_facet Sánchez M.
Otazú M.
Furtenbach P.
Piñeyro M.
author_sort Sánchez M.
collection DOAJ
description Prolactinoma is the most common pituitary tumor, with clinical presentations varying according to sex, age of onset, tumor size, and prolactin (PRL) levels. These tumors are rare in the pediatric and adolescent populations. Hyperprolactinemia leads to hypogonadotropic hypogonadism, resulting in reproductive, metabolic, sexual, and skeletal consequences that can affect puberty development. Here, we present the case of a 23-year-old male patient diagnosed with arrested puberty secondary to a macroprolactinoma. The clinical presentation, diagnostic approach, therapeutic management, and a literature review are discussed.
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series Case Reports in Endocrinology
spelling doaj-art-ac255f319c964138ac8854e6c73e90832025-02-08T00:00:05ZengWileyCase Reports in Endocrinology2090-651X2025-01-01202510.1155/crie/5388529Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature ReviewSánchez M.0Otazú M.1Furtenbach P.2Piñeyro M.3Unidad Académica de Endocrinología y MetabolismoUnidad Académica de Endocrinología y MetabolismoUnidad Académica de Endocrinología y MetabolismoUnidad Académica de Endocrinología y MetabolismoProlactinoma is the most common pituitary tumor, with clinical presentations varying according to sex, age of onset, tumor size, and prolactin (PRL) levels. These tumors are rare in the pediatric and adolescent populations. Hyperprolactinemia leads to hypogonadotropic hypogonadism, resulting in reproductive, metabolic, sexual, and skeletal consequences that can affect puberty development. Here, we present the case of a 23-year-old male patient diagnosed with arrested puberty secondary to a macroprolactinoma. The clinical presentation, diagnostic approach, therapeutic management, and a literature review are discussed.http://dx.doi.org/10.1155/crie/5388529
spellingShingle Sánchez M.
Otazú M.
Furtenbach P.
Piñeyro M.
Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review
Case Reports in Endocrinology
title Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review
title_full Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review
title_fullStr Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review
title_full_unstemmed Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review
title_short Arrested Puberty in a Young Adult With a Macroprolactinoma: Case Report and Literature Review
title_sort arrested puberty in a young adult with a macroprolactinoma case report and literature review
url http://dx.doi.org/10.1155/crie/5388529
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AT otazum arrestedpubertyinayoungadultwithamacroprolactinomacasereportandliteraturereview
AT furtenbachp arrestedpubertyinayoungadultwithamacroprolactinomacasereportandliteraturereview
AT pineyrom arrestedpubertyinayoungadultwithamacroprolactinomacasereportandliteraturereview