Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)

Aim of the Review. To characterize the main points of the reports devoted to the functional gastrointestinal disorders presented at the International Congress on Neurogastroenterology and Motility (Bologna, 2012).Key points. Functional constipation is widely spread in the population. The mechanisms...

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Main Authors: A. A. Sheptulin, M. A. Vize-Khripunova
Format: Article
Language:Russian
Published: Gastro LLC 2013-03-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/1188
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author A. A. Sheptulin
M. A. Vize-Khripunova
author_facet A. A. Sheptulin
M. A. Vize-Khripunova
author_sort A. A. Sheptulin
collection DOAJ
description Aim of the Review. To characterize the main points of the reports devoted to the functional gastrointestinal disorders presented at the International Congress on Neurogastroenterology and Motility (Bologna, 2012).Key points. Functional constipation is widely spread in the population. The mechanisms of cardiotoxic effect of cisapride and tegaserod were demonstrated and the safety of the administration of prucalopride was assessed. Currently the new pathogenic mechanisms of the irritable bowel syndrome (IBS) are under active study: the role of the infection, the violation of the intestinal mucosa permeability, the immune shifts, the reduction in the bile acids resorption etc.Conclusion. IBS is not considered as purely functional disease, it is recognized as multifactorial disease.
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-ad1b475b33b241c6b515e0076355cafc2025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732013-03-012318891772Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)A. A. Sheptulin0M. A. Vize-Khripunova1I.M. Sechenov First Moscow State Medical UniversityUlyanovsk State UniversityAim of the Review. To characterize the main points of the reports devoted to the functional gastrointestinal disorders presented at the International Congress on Neurogastroenterology and Motility (Bologna, 2012).Key points. Functional constipation is widely spread in the population. The mechanisms of cardiotoxic effect of cisapride and tegaserod were demonstrated and the safety of the administration of prucalopride was assessed. Currently the new pathogenic mechanisms of the irritable bowel syndrome (IBS) are under active study: the role of the infection, the violation of the intestinal mucosa permeability, the immune shifts, the reduction in the bile acids resorption etc.Conclusion. IBS is not considered as purely functional disease, it is recognized as multifactorial disease.https://www.gastro-j.ru/jour/article/view/1188functional constipationirritable bowel syndromepathogenesis
spellingShingle A. A. Sheptulin
M. A. Vize-Khripunova
Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
functional constipation
irritable bowel syndrome
pathogenesis
title Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)
title_full Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)
title_fullStr Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)
title_full_unstemmed Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)
title_short Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)
title_sort discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the international congress on neurogastroenterology and motility bologna 2012
topic functional constipation
irritable bowel syndrome
pathogenesis
url https://www.gastro-j.ru/jour/article/view/1188
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AT mavizekhripunova discussionoftheproblemoffunctionalconstipationandirritablebowelsyndromeinthereportsoftheinternationalcongressonneurogastroenterologyandmotilitybologna2012