Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)
Aim of the Review. To characterize the main points of the reports devoted to the functional gastrointestinal disorders presented at the International Congress on Neurogastroenterology and Motility (Bologna, 2012).Key points. Functional constipation is widely spread in the population. The mechanisms...
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Gastro LLC
2013-03-01
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Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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Online Access: | https://www.gastro-j.ru/jour/article/view/1188 |
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author | A. A. Sheptulin M. A. Vize-Khripunova |
author_facet | A. A. Sheptulin M. A. Vize-Khripunova |
author_sort | A. A. Sheptulin |
collection | DOAJ |
description | Aim of the Review. To characterize the main points of the reports devoted to the functional gastrointestinal disorders presented at the International Congress on Neurogastroenterology and Motility (Bologna, 2012).Key points. Functional constipation is widely spread in the population. The mechanisms of cardiotoxic effect of cisapride and tegaserod were demonstrated and the safety of the administration of prucalopride was assessed. Currently the new pathogenic mechanisms of the irritable bowel syndrome (IBS) are under active study: the role of the infection, the violation of the intestinal mucosa permeability, the immune shifts, the reduction in the bile acids resorption etc.Conclusion. IBS is not considered as purely functional disease, it is recognized as multifactorial disease. |
format | Article |
id | doaj-art-ad1b475b33b241c6b515e0076355cafc |
institution | Kabale University |
issn | 1382-4376 2658-6673 |
language | Russian |
publishDate | 2013-03-01 |
publisher | Gastro LLC |
record_format | Article |
series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
spelling | doaj-art-ad1b475b33b241c6b515e0076355cafc2025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732013-03-012318891772Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012)A. A. Sheptulin0M. A. Vize-Khripunova1I.M. Sechenov First Moscow State Medical UniversityUlyanovsk State UniversityAim of the Review. To characterize the main points of the reports devoted to the functional gastrointestinal disorders presented at the International Congress on Neurogastroenterology and Motility (Bologna, 2012).Key points. Functional constipation is widely spread in the population. The mechanisms of cardiotoxic effect of cisapride and tegaserod were demonstrated and the safety of the administration of prucalopride was assessed. Currently the new pathogenic mechanisms of the irritable bowel syndrome (IBS) are under active study: the role of the infection, the violation of the intestinal mucosa permeability, the immune shifts, the reduction in the bile acids resorption etc.Conclusion. IBS is not considered as purely functional disease, it is recognized as multifactorial disease.https://www.gastro-j.ru/jour/article/view/1188functional constipationirritable bowel syndromepathogenesis |
spellingShingle | A. A. Sheptulin M. A. Vize-Khripunova Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012) Российский журнал гастроэнтерологии, гепатологии, колопроктологии functional constipation irritable bowel syndrome pathogenesis |
title | Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012) |
title_full | Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012) |
title_fullStr | Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012) |
title_full_unstemmed | Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012) |
title_short | Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012) |
title_sort | discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the international congress on neurogastroenterology and motility bologna 2012 |
topic | functional constipation irritable bowel syndrome pathogenesis |
url | https://www.gastro-j.ru/jour/article/view/1188 |
work_keys_str_mv | AT aasheptulin discussionoftheproblemoffunctionalconstipationandirritablebowelsyndromeinthereportsoftheinternationalcongressonneurogastroenterologyandmotilitybologna2012 AT mavizekhripunova discussionoftheproblemoffunctionalconstipationandirritablebowelsyndromeinthereportsoftheinternationalcongressonneurogastroenterologyandmotilitybologna2012 |