Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients
[Objective] To analyze urogenital Mycoplasma hominis (Mh) and Ureaplasma urealyticum (Uu) infections and drug sensitivity, providing a rationale for choosing antibiotics in clinical practice. [Methods] Clinical data were collected from 296 patients with Mycoplasma infections who visited the First Ho...
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editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2025-01-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
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| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.01.003 |
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| _version_ | 1825199596268158976 |
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| author | CHEN Junwei HUANG Sheng QIU Wei XIAO Yupeng |
| author_facet | CHEN Junwei HUANG Sheng QIU Wei XIAO Yupeng |
| author_sort | CHEN Junwei |
| collection | DOAJ |
| description | [Objective] To analyze urogenital Mycoplasma hominis (Mh) and Ureaplasma urealyticum (Uu) infections and drug sensitivity, providing a rationale for choosing antibiotics in clinical practice. [Methods] Clinical data were collected from 296 patients with Mycoplasma infections who visited the First Hospital of Putian City from September 2022 to August 2023. The patients′age, gender and the clinical symptoms were analyzed. Urogenital specimen from patients was cultured for isolation and identification of Uu and Mh. [Results] Among 256 women and 40 men with mycoplasma infections, patients aged 31~40 years old accounted for 40.54%. The rate of Mycoplasma infections did not differ significantly between males and femlaes among all age groups (all P>0.05). Over 55% of the patients with Mycoplasma infections had clinical symptoms (χ2=5.68, P<0.05 vs. no symptoms). Patients with Uu and Mh infections were 238 cases (80.41%) and 5 cases (1.69%), respectively. Fifty-three cases (17.91%) were infected with both Mh+Uu. The positive rates of Uu and Uu+Mh infections were significantly higher in female patients than in male patients (χ2Uu=11.27, χ2Uu+Mh=10.09, P<0.05). In Mh positive patients, Mh was sensitive to both doxycycline and minocycline with a sensitive rate of 100%, but resistant to erythromycin and ciprofloxacin. In Mh+Uu positive patients, the sensitivity rates of doxycycline, minocycline and josamycin were over 90%, but resistant to erythromycin. In Uu positive patients, the sensitivity rates of doxycycline and minocycline were 100% and 99.58%, respectively, and the resistance rate of ciprofloxacin was 76.90%. [Conclusions] Females are more likely to have urogenital tract mycoplasma infections than males, and Uu is the main pathogen. The three types of infections are sensitive to doxycycline and minocycline. In clinical practice, the choosing antimicrobial drugs should be based on the type of infection and the sensitivity to the drugs. |
| format | Article |
| id | doaj-art-ad35243a87704643886e49a8dd6fec6d |
| institution | Kabale University |
| issn | 1674-8468 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj-art-ad35243a87704643886e49a8dd6fec6d2025-02-08T03:48:35Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682025-01-01321162210.3969/j.issn.1674-8468.2025.01.003Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patientsCHEN Junwei0HUANG Sheng1QIU Wei2XIAO Yupeng3Department of Clinical Laboratory, The First Hospital of Putian City, Putian 351100, ChinaDepartment of Clinical Laboratory, The First Hospital of Putian City, Putian 351100, ChinaDepartment of Clinical Laboratory, The First Hospital of Putian City, Putian 351100, ChinaDepartment of Clinical Laboratory, The First Hospital of Putian City, Putian 351100, China[Objective] To analyze urogenital Mycoplasma hominis (Mh) and Ureaplasma urealyticum (Uu) infections and drug sensitivity, providing a rationale for choosing antibiotics in clinical practice. [Methods] Clinical data were collected from 296 patients with Mycoplasma infections who visited the First Hospital of Putian City from September 2022 to August 2023. The patients′age, gender and the clinical symptoms were analyzed. Urogenital specimen from patients was cultured for isolation and identification of Uu and Mh. [Results] Among 256 women and 40 men with mycoplasma infections, patients aged 31~40 years old accounted for 40.54%. The rate of Mycoplasma infections did not differ significantly between males and femlaes among all age groups (all P>0.05). Over 55% of the patients with Mycoplasma infections had clinical symptoms (χ2=5.68, P<0.05 vs. no symptoms). Patients with Uu and Mh infections were 238 cases (80.41%) and 5 cases (1.69%), respectively. Fifty-three cases (17.91%) were infected with both Mh+Uu. The positive rates of Uu and Uu+Mh infections were significantly higher in female patients than in male patients (χ2Uu=11.27, χ2Uu+Mh=10.09, P<0.05). In Mh positive patients, Mh was sensitive to both doxycycline and minocycline with a sensitive rate of 100%, but resistant to erythromycin and ciprofloxacin. In Mh+Uu positive patients, the sensitivity rates of doxycycline, minocycline and josamycin were over 90%, but resistant to erythromycin. In Uu positive patients, the sensitivity rates of doxycycline and minocycline were 100% and 99.58%, respectively, and the resistance rate of ciprofloxacin was 76.90%. [Conclusions] Females are more likely to have urogenital tract mycoplasma infections than males, and Uu is the main pathogen. The three types of infections are sensitive to doxycycline and minocycline. In clinical practice, the choosing antimicrobial drugs should be based on the type of infection and the sensitivity to the drugs.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.01.003mycoplasma infectionmycoplasma hominisureaplasma urealyticumantibioticresistance |
| spellingShingle | CHEN Junwei HUANG Sheng QIU Wei XIAO Yupeng Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients Pifu-xingbing zhenliaoxue zazhi mycoplasma infection mycoplasma hominis ureaplasma urealyticum antibiotic resistance |
| title | Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients |
| title_full | Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients |
| title_fullStr | Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients |
| title_full_unstemmed | Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients |
| title_short | Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients |
| title_sort | analyses of urogenital mycoplasma hominis and ureaplasma urealyticum infections and drug sensitivity in 296 patients |
| topic | mycoplasma infection mycoplasma hominis ureaplasma urealyticum antibiotic resistance |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.01.003 |
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