Recent research progress on metal ions and metal-based nanomaterials in tumor therapy
Tumors, as a disease that seriously threatens human health, have always been a major challenge in the field of medicine. Currently, the main methods of tumor treatment include surgery, radiotherapy, chemotherapy, etc., but these traditional treatment methods often have certain limitations. In additi...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-02-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2025.1550089/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825206741513535488 |
|---|---|
| author | Yongcheng Xu Aikebaier Reheman Wenhua Feng Wenhua Feng Wenhua Feng |
| author_facet | Yongcheng Xu Aikebaier Reheman Wenhua Feng Wenhua Feng Wenhua Feng |
| author_sort | Yongcheng Xu |
| collection | DOAJ |
| description | Tumors, as a disease that seriously threatens human health, have always been a major challenge in the field of medicine. Currently, the main methods of tumor treatment include surgery, radiotherapy, chemotherapy, etc., but these traditional treatment methods often have certain limitations. In addition, tumor recurrence and metastasis are also difficult problems faced in clinical treatment. In this context, the importance of metal-based nanomaterials in tumor therapy is increasingly highlighted. Metal-based nanomaterials possess unique physical, chemical, and biological properties, providing new ideas and methods for tumor treatment. Metal-based nanomaterials can achieve targeted therapy for tumors through various mechanisms, reducing damage to normal tissues; they can also serve as drug carriers, improving the stability and bioavailability of drugs; at the same time, some metal-based nanomaterials also have photothermal, photodynamic, and other characteristics, which can be used for phototherapy of tumors. This review examines the latest advances in the application of metal-based nanomaterials in tumor therapy within past 5 years, and presents prospective insights into the future applications. |
| format | Article |
| id | doaj-art-adafbab93f814979b176c96fc356df2a |
| institution | Kabale University |
| issn | 2296-4185 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj-art-adafbab93f814979b176c96fc356df2a2025-02-07T06:49:46ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-02-011310.3389/fbioe.2025.15500891550089Recent research progress on metal ions and metal-based nanomaterials in tumor therapyYongcheng Xu0Aikebaier Reheman1Wenhua Feng2Wenhua Feng3Wenhua Feng4The Second School of Clinical Medicine, Shenyang Medical College, Shenyang, ChinaFujian Key Laboratory of Toxicant and Drug Toxicology, Medical College, Ningde Normal University, Ningde, Fujian, ChinaDepartment of Human Anatomy, School of Basic Medicine, Shenyang Medical College, Shenyang, ChinaLiaoning Province Key Laboratory for Phenomics of Human Ethnic Specificity and Critical Illness, Shenyang, ChinaShenyang Key Laboratory for Phenomics, Shenyang Medical College, Shenyang, ChinaTumors, as a disease that seriously threatens human health, have always been a major challenge in the field of medicine. Currently, the main methods of tumor treatment include surgery, radiotherapy, chemotherapy, etc., but these traditional treatment methods often have certain limitations. In addition, tumor recurrence and metastasis are also difficult problems faced in clinical treatment. In this context, the importance of metal-based nanomaterials in tumor therapy is increasingly highlighted. Metal-based nanomaterials possess unique physical, chemical, and biological properties, providing new ideas and methods for tumor treatment. Metal-based nanomaterials can achieve targeted therapy for tumors through various mechanisms, reducing damage to normal tissues; they can also serve as drug carriers, improving the stability and bioavailability of drugs; at the same time, some metal-based nanomaterials also have photothermal, photodynamic, and other characteristics, which can be used for phototherapy of tumors. This review examines the latest advances in the application of metal-based nanomaterials in tumor therapy within past 5 years, and presents prospective insights into the future applications.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1550089/fullmetal-based nanomaterialstumor therapyferroptosiscalcium overloadcuproptosisimmunotherapy |
| spellingShingle | Yongcheng Xu Aikebaier Reheman Wenhua Feng Wenhua Feng Wenhua Feng Recent research progress on metal ions and metal-based nanomaterials in tumor therapy Frontiers in Bioengineering and Biotechnology metal-based nanomaterials tumor therapy ferroptosis calcium overload cuproptosis immunotherapy |
| title | Recent research progress on metal ions and metal-based nanomaterials in tumor therapy |
| title_full | Recent research progress on metal ions and metal-based nanomaterials in tumor therapy |
| title_fullStr | Recent research progress on metal ions and metal-based nanomaterials in tumor therapy |
| title_full_unstemmed | Recent research progress on metal ions and metal-based nanomaterials in tumor therapy |
| title_short | Recent research progress on metal ions and metal-based nanomaterials in tumor therapy |
| title_sort | recent research progress on metal ions and metal based nanomaterials in tumor therapy |
| topic | metal-based nanomaterials tumor therapy ferroptosis calcium overload cuproptosis immunotherapy |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2025.1550089/full |
| work_keys_str_mv | AT yongchengxu recentresearchprogressonmetalionsandmetalbasednanomaterialsintumortherapy AT aikebaierreheman recentresearchprogressonmetalionsandmetalbasednanomaterialsintumortherapy AT wenhuafeng recentresearchprogressonmetalionsandmetalbasednanomaterialsintumortherapy AT wenhuafeng recentresearchprogressonmetalionsandmetalbasednanomaterialsintumortherapy AT wenhuafeng recentresearchprogressonmetalionsandmetalbasednanomaterialsintumortherapy |