Cytokine-armed oncolytic herpes simplex viruses: a game-changer in cancer immunotherapy?
Cytokines are small proteins that regulate the growth and functional activity of immune cells, and several have been approved for cancer therapy. Oncolytic viruses are agents that mediate antitumor activity by directly killing tumor cells and inducing immune responses. Talimogene laherparepvec is an...
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Main Authors: | Howard L Kaufman, Hongbin Wang, Dipongkor Saha, Samuel D Rabkin, Mia Borlongan, Uyen Le, Hans J Nauwynck |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2024-05-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/12/5/e008025.full |
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