Efficacy of silymarinum at chronic diffuse liver diseases
The aim of review. To present modern data of foreign literature on efficacy of preparation of Silybum marianum – silymarinum at patients with alcoholinduced liver disease, non-alcoholic steatohepatosis and primary biliary cirrhosis.Original positions. Analysis of literary data demonstrated, that sil...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2011-09-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1452 |
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| author | A. V. Matvieiev E. I. Konyaeva N. V. Matvieieva |
| author_facet | A. V. Matvieiev E. I. Konyaeva N. V. Matvieieva |
| author_sort | A. V. Matvieiev |
| collection | DOAJ |
| description | The aim of review. To present modern data of foreign literature on efficacy of preparation of Silybum marianum – silymarinum at patients with alcoholinduced liver disease, non-alcoholic steatohepatosis and primary biliary cirrhosis.Original positions. Analysis of literary data demonstrated, that silymarinum is a safe pharmaceutical and, despite of a plenty of clinical and experimental publications, its efficacy at alcoholic liver disease and primary biliary cirrhosis requires further studying as series of systematic reviews and metaanalyses are subject for discussion due to the absence of uniform methodological approaches, application of drugs with different pharmakokinetics and because of ignoring of evidencebased medicine requirements.Conclusion. Application of the uniform silymarinum standard and carrying out of further investigations adhering to requirements of evidence-based medicine, should finally resolve present contradictions in assessment of efficacy of standardized silymarinum in patients with alcoholic liver disease, non-alcoholic steatohepatosis and primary biliary cirrhosis. |
| format | Article |
| id | doaj-art-af1140e0000749d1b693f33d6af69643 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2011-09-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-af1140e0000749d1b693f33d6af696432025-02-10T16:14:31ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732011-09-012156469986Efficacy of silymarinum at chronic diffuse liver diseasesA. V. Matvieiev0E. I. Konyaeva1N. V. Matvieieva2Государственное учреждение «Крымский государственный медицинский университет им. С.И. Георгиевского Министерства здравоохранения Украины»Государственное учреждение «Крымский государственный медицинский университет им. С.И. Георгиевского Министерства здравоохранения Украины»Государственное учреждение «Крымский государственный медицинский университет им. С.И. Георгиевского Министерства здравоохранения Украины»The aim of review. To present modern data of foreign literature on efficacy of preparation of Silybum marianum – silymarinum at patients with alcoholinduced liver disease, non-alcoholic steatohepatosis and primary biliary cirrhosis.Original positions. Analysis of literary data demonstrated, that silymarinum is a safe pharmaceutical and, despite of a plenty of clinical and experimental publications, its efficacy at alcoholic liver disease and primary biliary cirrhosis requires further studying as series of systematic reviews and metaanalyses are subject for discussion due to the absence of uniform methodological approaches, application of drugs with different pharmakokinetics and because of ignoring of evidencebased medicine requirements.Conclusion. Application of the uniform silymarinum standard and carrying out of further investigations adhering to requirements of evidence-based medicine, should finally resolve present contradictions in assessment of efficacy of standardized silymarinum in patients with alcoholic liver disease, non-alcoholic steatohepatosis and primary biliary cirrhosis.https://www.gastro-j.ru/jour/article/view/1452silymarinumthistlealcohol-induced diseaselivercirrhosisnon-alcoholic steatohepatosis |
| spellingShingle | A. V. Matvieiev E. I. Konyaeva N. V. Matvieieva Efficacy of silymarinum at chronic diffuse liver diseases Российский журнал гастроэнтерологии, гепатологии, колопроктологии silymarinum thistle alcohol-induced disease liver cirrhosis non-alcoholic steatohepatosis |
| title | Efficacy of silymarinum at chronic diffuse liver diseases |
| title_full | Efficacy of silymarinum at chronic diffuse liver diseases |
| title_fullStr | Efficacy of silymarinum at chronic diffuse liver diseases |
| title_full_unstemmed | Efficacy of silymarinum at chronic diffuse liver diseases |
| title_short | Efficacy of silymarinum at chronic diffuse liver diseases |
| title_sort | efficacy of silymarinum at chronic diffuse liver diseases |
| topic | silymarinum thistle alcohol-induced disease liver cirrhosis non-alcoholic steatohepatosis |
| url | https://www.gastro-j.ru/jour/article/view/1452 |
| work_keys_str_mv | AT avmatvieiev efficacyofsilymarinumatchronicdiffuseliverdiseases AT eikonyaeva efficacyofsilymarinumatchronicdiffuseliverdiseases AT nvmatvieieva efficacyofsilymarinumatchronicdiffuseliverdiseases |