Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation
Highland barley β-glucan (HBG) has attracted increasing attention due to its excellent biological activities. However, the effects of HBG on gut flora and metabolites are unknown. Therefore, the effects of HBG on the gut microbiota during fermentation were analyzed by 16 s rRNA sequencing and untarg...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157524009775 |
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| author | Yinchen Ge Jiaci Liu Huacheng Tang Yanqing Zang Yang Cao |
| author_facet | Yinchen Ge Jiaci Liu Huacheng Tang Yanqing Zang Yang Cao |
| author_sort | Yinchen Ge |
| collection | DOAJ |
| description | Highland barley β-glucan (HBG) has attracted increasing attention due to its excellent biological activities. However, the effects of HBG on gut flora and metabolites are unknown. Therefore, the effects of HBG on the gut microbiota during fermentation were analyzed by 16 s rRNA sequencing and untargeted metabolomics. The results showed that HBG could enrich microbial diversity, increase the abundance of beneficial bacteria, and inhibit the biology of pathogenic bacteria. In addition, HBG increased the content of short-chain fatty acids and decreased fermentation broth pH. Metabolomics analyses showed that HBG also increased the content of beneficial metabolites such as taurine and affected amino acid metabolism, among other pathways. This study lays the foundation for the application of HBG in functional foods. |
| format | Article |
| id | doaj-art-b0a529b700ea4c56a11ed8d2d1629592 |
| institution | Kabale University |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-b0a529b700ea4c56a11ed8d2d16295922025-02-12T05:31:55ZengElsevierFood Chemistry: X2590-15752025-01-0125102089Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentationYinchen Ge0Jiaci Liu1Huacheng Tang2Yanqing Zang3Yang Cao4College of Food Science and Engineering, Heilongjiang Bayi Agriculture University, Daqing, Heilongjiang 163319, ChinaCollege of Food Science and Engineering, Heilongjiang Bayi Agriculture University, Daqing, Heilongjiang 163319, ChinaCollege of Food Science and Engineering, Heilongjiang Bayi Agriculture University, Daqing, Heilongjiang 163319, China; Chinese National Engineering Research Center, Daqing, Heilongjiang 163319, ChinaCollege of Food Science and Engineering, Heilongjiang Bayi Agriculture University, Daqing, Heilongjiang 163319, China; Chinese National Engineering Research Center, Daqing, Heilongjiang 163319, China; Corresponding author at: Chinese National Engineering Research Center, Daqing, Heilongjiang 163319, China.Chinese National Engineering Research Center, Daqing, Heilongjiang 163319, China; College of Animal Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang, 163319, China; Corresponding author at: Chinese National Engineering Research Center, Daqing, Heilongjiang 163319, China.Highland barley β-glucan (HBG) has attracted increasing attention due to its excellent biological activities. However, the effects of HBG on gut flora and metabolites are unknown. Therefore, the effects of HBG on the gut microbiota during fermentation were analyzed by 16 s rRNA sequencing and untargeted metabolomics. The results showed that HBG could enrich microbial diversity, increase the abundance of beneficial bacteria, and inhibit the biology of pathogenic bacteria. In addition, HBG increased the content of short-chain fatty acids and decreased fermentation broth pH. Metabolomics analyses showed that HBG also increased the content of beneficial metabolites such as taurine and affected amino acid metabolism, among other pathways. This study lays the foundation for the application of HBG in functional foods.http://www.sciencedirect.com/science/article/pii/S2590157524009775Highland barley β-glucanFecal microbiotaMetabolitesSCFAs |
| spellingShingle | Yinchen Ge Jiaci Liu Huacheng Tang Yanqing Zang Yang Cao Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation Food Chemistry: X Highland barley β-glucan Fecal microbiota Metabolites SCFAs |
| title | Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation |
| title_full | Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation |
| title_fullStr | Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation |
| title_full_unstemmed | Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation |
| title_short | Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation |
| title_sort | effects of highland barley β glucan on gut microbiota composition and metabolism in vitro fermentation |
| topic | Highland barley β-glucan Fecal microbiota Metabolites SCFAs |
| url | http://www.sciencedirect.com/science/article/pii/S2590157524009775 |
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