Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis
Introduction: Despite the evident impact of ultrasonography on diagnosis in acute care settings, there is still a great deal of uncertainty regarding its accuracy. This study aimed to assess the diagnostic performance of lung ultrasonography (LUS) for the identification of acute heart failure in pa...
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Shahid Beheshti University of Medical Sciences
2025-01-01
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| Series: | Archives of Academic Emergency Medicine |
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| Online Access: | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2555 |
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| author | Erfan Rahmani Masoud Farrokhi Mehrdad Farrokhi Shadi Nouri Atousa Moghadam Fard Behnam Hoorshad Ramin Atighi Erfan Ghadirzadeh Michael Tajik Habibollah Afshang Aida Naseri Mohadeseh Asoudehfard Shiva Samami Kojidi Arsham Ebnemehdi Mehdi Rezaei Maziar Daneshvar Amirali Makhmalbaf Sepideh Hassanpour Khodaei Shirin Farsi Saber Barazandeh Rad Fateme Nozari Pouya Rezaei Negar Babapour Salman Delavar Babak Goodarzy Lida Zare Lahijan Sanam Mohammadzadeh Helena Mehran Fatemeh Gheibi Ramtin Shemshadigolafzani Behnaz Dalvandi Amir Abderam |
| author_facet | Erfan Rahmani Masoud Farrokhi Mehrdad Farrokhi Shadi Nouri Atousa Moghadam Fard Behnam Hoorshad Ramin Atighi Erfan Ghadirzadeh Michael Tajik Habibollah Afshang Aida Naseri Mohadeseh Asoudehfard Shiva Samami Kojidi Arsham Ebnemehdi Mehdi Rezaei Maziar Daneshvar Amirali Makhmalbaf Sepideh Hassanpour Khodaei Shirin Farsi Saber Barazandeh Rad Fateme Nozari Pouya Rezaei Negar Babapour Salman Delavar Babak Goodarzy Lida Zare Lahijan Sanam Mohammadzadeh Helena Mehran Fatemeh Gheibi Ramtin Shemshadigolafzani Behnaz Dalvandi Amir Abderam |
| author_sort | Erfan Rahmani |
| collection | DOAJ |
| description |
Introduction: Despite the evident impact of ultrasonography on diagnosis in acute care settings, there is still a great deal of uncertainty regarding its accuracy. This study aimed to assess the diagnostic performance of lung ultrasonography (LUS) for the identification of acute heart failure in patients with suggestive manifestations.
Methods: Medline, Scopus, and Web of Science were comprehensively searched from their inception to November 2024 to identify original studies investigating accuracy of LUS for diagnosis of heart failure. Data extraction and quality assessment were performed by two independent reviewers. The statistical analysis for pooling the results of diagnostic performance parameters was conducted using Stata and Meta-DiSc softwares.
Results: Thirty-eight included studies in this meta-analysis were published between 2006 and 2024, encompassing a total of 6,783 patients. There was significant heterogeneity between included studies with respect to sensitivity (I2=92.51 and P<0.01) and specificity (I2=93.79 and P<0.01). The pooled sensitivity, specificity, and accuracy of LUS for detection of heart failure were 0.92 (95% CI, 0.87-0.95), 0.90 (95% CI, 0.86-0.93), and 0.96 (95% CI, 0.94-0.98), respectively. In addition, pooled positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were 7.87 (95% CI, 5.60-11.07), 0.14 (95% CI, 0.10-0.19), and 70.74 (95% CI, 41.98-119.21), respectively.
Conclusion: Our meta-analysis demonstrates that LUS is a highly practical imaging for diagnosing acute heart failure, with excellent sensitivity, specificity, and accuracy. It is particularly valuable for excluding the heart failure when the result is negative. However, the influence of outlier and influential studies warrants caution, and future studies should aim to further validate these findings in diverse clinical contexts.
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| format | Article |
| id | doaj-art-b0bfab14f1b0465b9f83b03e37d839ca |
| institution | Kabale University |
| issn | 2645-4904 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Archives of Academic Emergency Medicine |
| spelling | doaj-art-b0bfab14f1b0465b9f83b03e37d839ca2025-02-11T20:47:48ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042025-01-0113110.22037/aaemj.v13i1.2555Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysisErfan RahmaniMasoud FarrokhiMehrdad Farrokhi0Shadi NouriAtousa Moghadam FardBehnam HoorshadRamin AtighiErfan GhadirzadehMichael TajikHabibollah AfshangAida NaseriMohadeseh AsoudehfardShiva Samami KojidiArsham EbnemehdiMehdi RezaeiMaziar DaneshvarAmirali MakhmalbafSepideh Hassanpour KhodaeiShirin FarsiSaber Barazandeh RadFateme NozariPouya RezaeiNegar BabapourSalman DelavarBabak GoodarzyLida Zare LahijanSanam MohammadzadehHelena MehranFatemeh GheibiRamtin ShemshadigolafzaniBehnaz DalvandiAmir AbderamShahid Beheshti University of Medical Sciences, Tehran, Iran Introduction: Despite the evident impact of ultrasonography on diagnosis in acute care settings, there is still a great deal of uncertainty regarding its accuracy. This study aimed to assess the diagnostic performance of lung ultrasonography (LUS) for the identification of acute heart failure in patients with suggestive manifestations. Methods: Medline, Scopus, and Web of Science were comprehensively searched from their inception to November 2024 to identify original studies investigating accuracy of LUS for diagnosis of heart failure. Data extraction and quality assessment were performed by two independent reviewers. The statistical analysis for pooling the results of diagnostic performance parameters was conducted using Stata and Meta-DiSc softwares. Results: Thirty-eight included studies in this meta-analysis were published between 2006 and 2024, encompassing a total of 6,783 patients. There was significant heterogeneity between included studies with respect to sensitivity (I2=92.51 and P<0.01) and specificity (I2=93.79 and P<0.01). The pooled sensitivity, specificity, and accuracy of LUS for detection of heart failure were 0.92 (95% CI, 0.87-0.95), 0.90 (95% CI, 0.86-0.93), and 0.96 (95% CI, 0.94-0.98), respectively. In addition, pooled positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were 7.87 (95% CI, 5.60-11.07), 0.14 (95% CI, 0.10-0.19), and 70.74 (95% CI, 41.98-119.21), respectively. Conclusion: Our meta-analysis demonstrates that LUS is a highly practical imaging for diagnosing acute heart failure, with excellent sensitivity, specificity, and accuracy. It is particularly valuable for excluding the heart failure when the result is negative. However, the influence of outlier and influential studies warrants caution, and future studies should aim to further validate these findings in diverse clinical contexts. https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2555DyspneaHeart FailureLungMeta-analysisUltrasonography |
| spellingShingle | Erfan Rahmani Masoud Farrokhi Mehrdad Farrokhi Shadi Nouri Atousa Moghadam Fard Behnam Hoorshad Ramin Atighi Erfan Ghadirzadeh Michael Tajik Habibollah Afshang Aida Naseri Mohadeseh Asoudehfard Shiva Samami Kojidi Arsham Ebnemehdi Mehdi Rezaei Maziar Daneshvar Amirali Makhmalbaf Sepideh Hassanpour Khodaei Shirin Farsi Saber Barazandeh Rad Fateme Nozari Pouya Rezaei Negar Babapour Salman Delavar Babak Goodarzy Lida Zare Lahijan Sanam Mohammadzadeh Helena Mehran Fatemeh Gheibi Ramtin Shemshadigolafzani Behnaz Dalvandi Amir Abderam Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis Archives of Academic Emergency Medicine Dyspnea Heart Failure Lung Meta-analysis Ultrasonography |
| title | Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis |
| title_full | Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis |
| title_fullStr | Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis |
| title_full_unstemmed | Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis |
| title_short | Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis |
| title_sort | accuracy of lung ultrasonography for diagnosis of heart failure a systematic review and meta analysis |
| topic | Dyspnea Heart Failure Lung Meta-analysis Ultrasonography |
| url | https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2555 |
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