Research progress on early intervention of postoperative scar
Scars, the final outcome of postoperative wound healing, can be classified into physiological scars and pathological scars. Following surgical procedures, dysregulation of the inflammatory response, abnormal mechanical forces surrounding the wound, and hypoxia within the scar tissue may lead to an o...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2025-01-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
| Subjects: | |
| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.01.012 |
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| Summary: | Scars, the final outcome of postoperative wound healing, can be classified into physiological scars and pathological scars. Following surgical procedures, dysregulation of the inflammatory response, abnormal mechanical forces surrounding the wound, and hypoxia within the scar tissue may lead to an overproliferation of fibroblasts in postoperative scars, resulting in excessive deposition of extracellular matrix and ultimately developing pathological scars. The emergence of pathological scars does not only negatively impact patients′ physical and mental well-being, but also significantly diminishes their quality of life. Because of the big challenge in the treatment of scars, early intervention strategies, such as vascular sealing, modulation of inflammatory factors, and tension reduction, can expedite the maturation process of postoperative scars while decreasing the incidence of pathological scars. This paper aims to overview the methods and mechanisms for early intervention of postoperative scars, including intraoperative tension reduction suture, reduction in postoperative pressure and injection therapy, laser, and topical medication, in order to provide valuable insights for related therapeutic approaches. |
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| ISSN: | 1674-8468 |