The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD

Epstein-Barr virus (EBV) can cause lymphoproliferative disorders (PTLD) in immunodeficiency individuals. The pathogenesis of EBV infection depends on its effective recognition and elimination. Our study investigated the effect of peripheral lymphocyte subsets (PLS) on the elimination of EBV.

Saved in:
Bibliographic Details
Main Authors: Wang Kedi, Xu Dongjiang, Gao Yan, Ma Kaihui, Zhao Wen
Format: Article
Language:English
Published: De Gruyter 2025-02-01
Series:Journal of Laboratory Medicine
Subjects:
Online Access:https://doi.org/10.1515/labmed-2024-0081
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823860521342861312
author Wang Kedi
Xu Dongjiang
Gao Yan
Ma Kaihui
Zhao Wen
author_facet Wang Kedi
Xu Dongjiang
Gao Yan
Ma Kaihui
Zhao Wen
author_sort Wang Kedi
collection DOAJ
description Epstein-Barr virus (EBV) can cause lymphoproliferative disorders (PTLD) in immunodeficiency individuals. The pathogenesis of EBV infection depends on its effective recognition and elimination. Our study investigated the effect of peripheral lymphocyte subsets (PLS) on the elimination of EBV.
format Article
id doaj-art-b63198999d124e338d987eb656d54c53
institution Kabale University
issn 2567-9430
2567-9449
language English
publishDate 2025-02-01
publisher De Gruyter
record_format Article
series Journal of Laboratory Medicine
spelling doaj-art-b63198999d124e338d987eb656d54c532025-02-10T13:24:33ZengDe GruyterJournal of Laboratory Medicine2567-94302567-94492025-02-01491384510.1515/labmed-2024-0081The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLDWang Kedi0Xu Dongjiang1Gao Yan2Ma Kaihui3Zhao Wen4Department of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Blood Transfusion, Beijing Jishuitan Hospital, Capital Medical University, Beijing, ChinaDepartment of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaEpstein-Barr virus (EBV) can cause lymphoproliferative disorders (PTLD) in immunodeficiency individuals. The pathogenesis of EBV infection depends on its effective recognition and elimination. Our study investigated the effect of peripheral lymphocyte subsets (PLS) on the elimination of EBV.https://doi.org/10.1515/labmed-2024-0081epstein-barr virusdnaperipheral lymphocyte subsetsliver transplantationptld
spellingShingle Wang Kedi
Xu Dongjiang
Gao Yan
Ma Kaihui
Zhao Wen
The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD
Journal of Laboratory Medicine
epstein-barr virus
dna
peripheral lymphocyte subsets
liver transplantation
ptld
title The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD
title_full The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD
title_fullStr The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD
title_full_unstemmed The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD
title_short The trend of Epstein-Barr virus DNA loads and CD8+ T lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with PTLD
title_sort trend of epstein barr virus dna loads and cd8 t lymphocyte numbers can predict the prognosis of pediatric liver transplant recipients with ptld
topic epstein-barr virus
dna
peripheral lymphocyte subsets
liver transplantation
ptld
url https://doi.org/10.1515/labmed-2024-0081
work_keys_str_mv AT wangkedi thetrendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT xudongjiang thetrendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT gaoyan thetrendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT makaihui thetrendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT zhaowen thetrendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT wangkedi trendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT xudongjiang trendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT gaoyan trendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT makaihui trendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld
AT zhaowen trendofepsteinbarrvirusdnaloadsandcd8tlymphocytenumberscanpredicttheprognosisofpediatriclivertransplantrecipientswithptld