An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups
OBJECTIVE: To validate the usability of “Beksaç Obstetrics Index” (BOI/BOIp) in the evaluation of different high risk pregnancy groups. STUDY DESIGN: This study is consisted of 3 groups of patients; 1) Pregnancies without MTHFR polymorphisms (n=65), 2) Pregnancies with methylenetetrahydrofolate re...
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Medical Network
2015-04-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/37 |
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| author | M. Sinan Beksaç Emine Aydın Mert Tuğral Ergün Karaağaoğlu |
| author_facet | M. Sinan Beksaç Emine Aydın Mert Tuğral Ergün Karaağaoğlu |
| author_sort | M. Sinan Beksaç |
| collection | DOAJ |
| description |
OBJECTIVE: To validate the usability of “Beksaç Obstetrics Index” (BOI/BOIp) in the evaluation of different high risk pregnancy groups.
STUDY DESIGN: This study is consisted of 3 groups of patients; 1) Pregnancies without MTHFR polymorphisms (n=65), 2) Pregnancies with methylenetetrahydrofolate reductase (MTHFR; homozygous or compound heterozygous) polymorphisms (n=140), 3) Pregnancies with “autoimmune antibody positivity” without any other type of hereditary thrombophilia (Anti-dsDNA, anti-phospholipid Ig G/M, anti-cardiolipin Ig G/M, ASMA, APA, ENA, anti-mitochondrial antibodies) (n=76). In this study, BOI which is (number of child +π/10)/Gravida is used in order to demonstrate the risk levels/scale of different high risk pregnancy groups.
RESULTS: The mean BOIp (±SD) values are 0,41±0,22; 0,29±0,21; and 0,40±0,23 for Control, MTHFR and Autoimmune groups respectively. We have demonstrated statistically significantly decreased BOIp level in MTHFR group compared to the other groups (p:0,002).
CONCLUSION: We have demonstrated that BOI/BOIp can be used in the assessment of risk levels of different high risk pregnancy groups.
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| format | Article |
| id | doaj-art-b644f3232efb475ab0159ac2ce0df173 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2015-04-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-b644f3232efb475ab0159ac2ce0df1732025-02-11T21:25:23ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182015-04-0121132An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” GroupsM. Sinan Beksaç0Emine Aydın1Mert Tuğral2Ergün Karaağaoğlu3Hacettepe University Medical Faculty Division of Perinatal Medicine, AnkaraHacettepe University Medical Faculty Division of Perinatal Medicine, AnkaraHacettepe University Medical Faculty Division of Perinatal Medicine, AnkaraHacettepe University Medical Faculty Department of Bioistatistics, Ankara OBJECTIVE: To validate the usability of “Beksaç Obstetrics Index” (BOI/BOIp) in the evaluation of different high risk pregnancy groups. STUDY DESIGN: This study is consisted of 3 groups of patients; 1) Pregnancies without MTHFR polymorphisms (n=65), 2) Pregnancies with methylenetetrahydrofolate reductase (MTHFR; homozygous or compound heterozygous) polymorphisms (n=140), 3) Pregnancies with “autoimmune antibody positivity” without any other type of hereditary thrombophilia (Anti-dsDNA, anti-phospholipid Ig G/M, anti-cardiolipin Ig G/M, ASMA, APA, ENA, anti-mitochondrial antibodies) (n=76). In this study, BOI which is (number of child +π/10)/Gravida is used in order to demonstrate the risk levels/scale of different high risk pregnancy groups. RESULTS: The mean BOIp (±SD) values are 0,41±0,22; 0,29±0,21; and 0,40±0,23 for Control, MTHFR and Autoimmune groups respectively. We have demonstrated statistically significantly decreased BOIp level in MTHFR group compared to the other groups (p:0,002). CONCLUSION: We have demonstrated that BOI/BOIp can be used in the assessment of risk levels of different high risk pregnancy groups. https://gorm.com.tr/index.php/GORM/article/view/37Perinatal morbidity & mortalityHigh risk pregnancyBeksac obstetrics index |
| spellingShingle | M. Sinan Beksaç Emine Aydın Mert Tuğral Ergün Karaağaoğlu An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups Gynecology Obstetrics & Reproductive Medicine Perinatal morbidity & mortality High risk pregnancy Beksac obstetrics index |
| title | An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups |
| title_full | An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups |
| title_fullStr | An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups |
| title_full_unstemmed | An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups |
| title_short | An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups |
| title_sort | obstetrics index for the assessment of risk levels of high risk pregnancy groups |
| topic | Perinatal morbidity & mortality High risk pregnancy Beksac obstetrics index |
| url | https://gorm.com.tr/index.php/GORM/article/view/37 |
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