Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus

OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD (LNG-IUD) on the proteoglycan composition of cervical mucus. STUDY DESIGN: This was a cross-sectional study that was conducted at a gynecology outpatient clinic of a University hospital for a six month...

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Main Authors: Yeşim Bayoğlu Tekin, Emine Seda Güvendağ Güven, Zihni Açar Yazıcı, Aynur Kırbaş, Figen Kır Şahin
Format: Article
Language:English
Published: Medical Network 2014-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
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Online Access:https://gorm.com.tr/index.php/GORM/article/view/164
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author Yeşim Bayoğlu Tekin
Emine Seda Güvendağ Güven
Zihni Açar Yazıcı
Aynur Kırbaş
Figen Kır Şahin
author_facet Yeşim Bayoğlu Tekin
Emine Seda Güvendağ Güven
Zihni Açar Yazıcı
Aynur Kırbaş
Figen Kır Şahin
author_sort Yeşim Bayoğlu Tekin
collection DOAJ
description OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD (LNG-IUD) on the proteoglycan composition of cervical mucus. STUDY DESIGN: This was a cross-sectional study that was conducted at a gynecology outpatient clinic of a University hospital for a six month period. The study participants were between 18-50 years old, using either Copper T or LNG-IUD for contraception. Cervical mucus samples were collected 7 days after the menstrual bleeding and the levels of hyaluronan (HA), heparin sulfate (HS) and sulfated-glycosaminoglycans (s-GAG) were evaluated. RESULTS: The levels of HA, HS and s-GAG in the Copper-T and LNG-IUD groups were higher than those of the controls. However, the difference was statistically significant only for s-GAG (p<0.001). CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effects on proteoglycan component of cervical mucus.
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institution Kabale University
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language English
publishDate 2014-12-01
publisher Medical Network
record_format Article
series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-ba426be67c9943c390b5bde8e3ba63312025-02-11T21:24:19ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182014-12-01203103Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical MucusYeşim Bayoğlu Tekin0Emine Seda Güvendağ Güven1Zihni Açar Yazıcı2Aynur Kırbaş3Figen Kır Şahin4Department of Gynecology and Obstetrics, Recep Tayyip Erdogan University, RizeDepartment of Gynecology and Obstetrics, Recep Tayyip Erdogan University, RizeDepartment of Microbiology, Recep Tayyip Erdogan University, RizeDepartment of Biochemistry School, Recep Tayyip Erdogan University, RizeDepartment of Gynecology and Obstetrics, Recep Tayyip Erdogan University, Rize OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD (LNG-IUD) on the proteoglycan composition of cervical mucus. STUDY DESIGN: This was a cross-sectional study that was conducted at a gynecology outpatient clinic of a University hospital for a six month period. The study participants were between 18-50 years old, using either Copper T or LNG-IUD for contraception. Cervical mucus samples were collected 7 days after the menstrual bleeding and the levels of hyaluronan (HA), heparin sulfate (HS) and sulfated-glycosaminoglycans (s-GAG) were evaluated. RESULTS: The levels of HA, HS and s-GAG in the Copper-T and LNG-IUD groups were higher than those of the controls. However, the difference was statistically significant only for s-GAG (p<0.001). CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effects on proteoglycan component of cervical mucus. https://gorm.com.tr/index.php/GORM/article/view/164Cervical mucusCopper T IUDLevonorgestrel IUD
spellingShingle Yeşim Bayoğlu Tekin
Emine Seda Güvendağ Güven
Zihni Açar Yazıcı
Aynur Kırbaş
Figen Kır Şahin
Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus
Gynecology Obstetrics & Reproductive Medicine
Cervical mucus
Copper T IUD
Levonorgestrel IUD
title Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus
title_full Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus
title_fullStr Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus
title_full_unstemmed Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus
title_short Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus
title_sort comparison of the effects of copper t and levonorgestrel iud on proteoglycan composition of cervical mucus
topic Cervical mucus
Copper T IUD
Levonorgestrel IUD
url https://gorm.com.tr/index.php/GORM/article/view/164
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