Insights into CSF-1/CSF-1R signaling: the role of macrophage in radiotherapy

Insights into CSF-1/CSF-1R signaling: the role of macrophage in radiotherapy

Macrophage plays an important role in homeostasis and immunity, and dysfunctional macrophage polarization is believed to be associated with the pathogenesis of tissue fibrosis and tumor progression. Colony stimulating factor-1 (CSF-1), a polypeptide chain cytokine, through its receptor (CSF-1R) regu...

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Bibliographic Details
Main Authors: Qingchao Shang, Pei Zhang, Xiao Lei, Lehui Du, Baolin Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
CSF-1
macrophage
radiotherapy
radiation-induced pulmonary fibrosis (RIPF)
tumor associate macrophages (TAM)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1530890/full
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