Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities
High molecular mass and poor solubility of Auricularia auricula polysaccharides (AAP) limit their physiological activity. This study employed ultrasonic degradation to address these challenges. Ultrasonic treatment reduced the molecular mass of AAP from 1 × 105 Da to 3.8 × 103–8 × 104 Da, enhanced h...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Food Chemistry: X |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157525000550 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823856693995372544 |
|---|---|
| author | Te Yu Yonggang Dai Zifei Wang Yang Gao Qiong Wu |
| author_facet | Te Yu Yonggang Dai Zifei Wang Yang Gao Qiong Wu |
| author_sort | Te Yu |
| collection | DOAJ |
| description | High molecular mass and poor solubility of Auricularia auricula polysaccharides (AAP) limit their physiological activity. This study employed ultrasonic degradation to address these challenges. Ultrasonic treatment reduced the molecular mass of AAP from 1 × 105 Da to 3.8 × 103–8 × 104 Da, enhanced hydroxyl group exposure, and significantly improved solubility, with dissolution time reduced to one-ninth of the pre-degradation level at 20 °C. The antioxidant activities of AAP were enhanced after ultrasonic degradation, with DPPH scavenging IC50 reduced from 3.58 mg/mL to 2.07 mg/mL and hydroxyl radical IC50 from 2.28 mg/mL to 1.77 mg/mL. Hypoglycemic effects were improved, with α-amylase and α-glucosidase inhibition rates increasing by 5.06 % and 5.81 %, respectively. Bile acid binding for MBS improved by 28.6 %, indicating ultrasonic degradation enhanced hypolipidemic activity. This study demonstrates ultrasonic degradation is a green, efficient method to improve AAP's functional properties, which broadens its applications in functional foods and health supplements. |
| format | Article |
| id | doaj-art-bb8a6d3df5b54944afc972dbf0a23885 |
| institution | Kabale University |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-bb8a6d3df5b54944afc972dbf0a238852025-02-12T05:32:35ZengElsevierFood Chemistry: X2590-15752025-01-0125102209Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activitiesTe Yu0Yonggang Dai1Zifei Wang2Yang Gao3Qiong Wu4Department of Food Science and Engineering, College of Food Science and Engineering, Changchun University, No.6543, Satellite Road, Changchun 130022, ChinaJilin Academy of Agricultural Sciences, Changchun, Jilin Province 130033, ChinaDepartment of Food Science and Engineering, College of Food Science and Engineering, Changchun University, No.6543, Satellite Road, Changchun 130022, ChinaJilin Academy of Agricultural Sciences, Changchun, Jilin Province 130033, ChinaDepartment of Food Science and Engineering, College of Food Science and Engineering, Changchun University, No.6543, Satellite Road, Changchun 130022, China; Corresponding author.High molecular mass and poor solubility of Auricularia auricula polysaccharides (AAP) limit their physiological activity. This study employed ultrasonic degradation to address these challenges. Ultrasonic treatment reduced the molecular mass of AAP from 1 × 105 Da to 3.8 × 103–8 × 104 Da, enhanced hydroxyl group exposure, and significantly improved solubility, with dissolution time reduced to one-ninth of the pre-degradation level at 20 °C. The antioxidant activities of AAP were enhanced after ultrasonic degradation, with DPPH scavenging IC50 reduced from 3.58 mg/mL to 2.07 mg/mL and hydroxyl radical IC50 from 2.28 mg/mL to 1.77 mg/mL. Hypoglycemic effects were improved, with α-amylase and α-glucosidase inhibition rates increasing by 5.06 % and 5.81 %, respectively. Bile acid binding for MBS improved by 28.6 %, indicating ultrasonic degradation enhanced hypolipidemic activity. This study demonstrates ultrasonic degradation is a green, efficient method to improve AAP's functional properties, which broadens its applications in functional foods and health supplements.http://www.sciencedirect.com/science/article/pii/S2590157525000550Auricularia auricula polysaccharidesUltrasonic degradationAntioxidant activityHypoglycemic activityHypolipidemic activityFunctional food |
| spellingShingle | Te Yu Yonggang Dai Zifei Wang Yang Gao Qiong Wu Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities Food Chemistry: X Auricularia auricula polysaccharides Ultrasonic degradation Antioxidant activity Hypoglycemic activity Hypolipidemic activity Functional food |
| title | Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities |
| title_full | Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities |
| title_fullStr | Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities |
| title_full_unstemmed | Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities |
| title_short | Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities |
| title_sort | ultrasound induced modifications of auricularia auricula polysaccharides implications for antioxidant and glucose lowering activities |
| topic | Auricularia auricula polysaccharides Ultrasonic degradation Antioxidant activity Hypoglycemic activity Hypolipidemic activity Functional food |
| url | http://www.sciencedirect.com/science/article/pii/S2590157525000550 |
| work_keys_str_mv | AT teyu ultrasoundinducedmodificationsofauriculariaauriculapolysaccharidesimplicationsforantioxidantandglucoseloweringactivities AT yonggangdai ultrasoundinducedmodificationsofauriculariaauriculapolysaccharidesimplicationsforantioxidantandglucoseloweringactivities AT zifeiwang ultrasoundinducedmodificationsofauriculariaauriculapolysaccharidesimplicationsforantioxidantandglucoseloweringactivities AT yanggao ultrasoundinducedmodificationsofauriculariaauriculapolysaccharidesimplicationsforantioxidantandglucoseloweringactivities AT qiongwu ultrasoundinducedmodificationsofauriculariaauriculapolysaccharidesimplicationsforantioxidantandglucoseloweringactivities |