Modern treatment methods of patients with liver metastases of colorectal cancer
Aim of investigation. Efficacy of the modern methods of treatment of liver metastases of colorectal cancer was estimated.Material and methods. Overall 117 patients have been included in the study with isolated metastatic liver involvement. Efficacy of liver resection, radio-frequency ablation (RFA),...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2013-07-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1201 |
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| author | Ye. N. Grebenkin V. D. Chhikvadze U. S. Stanoyevich Ye. I. Dekhissi |
| author_facet | Ye. N. Grebenkin V. D. Chhikvadze U. S. Stanoyevich Ye. I. Dekhissi |
| author_sort | Ye. N. Grebenkin |
| collection | DOAJ |
| description | Aim of investigation. Efficacy of the modern methods of treatment of liver metastases of colorectal cancer was estimated.Material and methods. Overall 117 patients have been included in the study with isolated metastatic liver involvement. Efficacy of liver resection, radio-frequency ablation (RFA), systemic and intra-arterial hepatic chemotherapy (IAHC) was studied.Results. The five-years general survival rate at liver resection was 33,3%, relapse-free – 22,2%, at RFA – 16,2 and 13,5% respectively. HACE allows to achieve higher rate of positive response, not increasing risk of generalization of process, but does not improve scores of remote survival rate in comparison to systemic chemotherapy.Conclusions. The most effective treatment method, allowing to achieve 33% of 5-year survival, is liver resection. |
| format | Article |
| id | doaj-art-bca1617f0b374c968b476b2413cc250d |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2013-07-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-bca1617f0b374c968b476b2413cc250d2025-02-10T16:14:32ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732013-07-012332832785Modern treatment methods of patients with liver metastases of colorectal cancerYe. N. Grebenkin0V. D. Chhikvadze1U. S. Stanoyevich2Ye. I. Dekhissi3Federal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian FederationFederal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian FederationFederal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian FederationFederal state-funded institution «Russian scientific center of roentgenoradiology» Ministry of healthcare of the Russian FederationAim of investigation. Efficacy of the modern methods of treatment of liver metastases of colorectal cancer was estimated.Material and methods. Overall 117 patients have been included in the study with isolated metastatic liver involvement. Efficacy of liver resection, radio-frequency ablation (RFA), systemic and intra-arterial hepatic chemotherapy (IAHC) was studied.Results. The five-years general survival rate at liver resection was 33,3%, relapse-free – 22,2%, at RFA – 16,2 and 13,5% respectively. HACE allows to achieve higher rate of positive response, not increasing risk of generalization of process, but does not improve scores of remote survival rate in comparison to systemic chemotherapy.Conclusions. The most effective treatment method, allowing to achieve 33% of 5-year survival, is liver resection.https://www.gastro-j.ru/jour/article/view/1201colorectal cancermetastasesresection of the liverradio-frequency ablationregional endarterial chemotherapy |
| spellingShingle | Ye. N. Grebenkin V. D. Chhikvadze U. S. Stanoyevich Ye. I. Dekhissi Modern treatment methods of patients with liver metastases of colorectal cancer Российский журнал гастроэнтерологии, гепатологии, колопроктологии colorectal cancer metastases resection of the liver radio-frequency ablation regional endarterial chemotherapy |
| title | Modern treatment methods of patients with liver metastases of colorectal cancer |
| title_full | Modern treatment methods of patients with liver metastases of colorectal cancer |
| title_fullStr | Modern treatment methods of patients with liver metastases of colorectal cancer |
| title_full_unstemmed | Modern treatment methods of patients with liver metastases of colorectal cancer |
| title_short | Modern treatment methods of patients with liver metastases of colorectal cancer |
| title_sort | modern treatment methods of patients with liver metastases of colorectal cancer |
| topic | colorectal cancer metastases resection of the liver radio-frequency ablation regional endarterial chemotherapy |
| url | https://www.gastro-j.ru/jour/article/view/1201 |
| work_keys_str_mv | AT yengrebenkin moderntreatmentmethodsofpatientswithlivermetastasesofcolorectalcancer AT vdchhikvadze moderntreatmentmethodsofpatientswithlivermetastasesofcolorectalcancer AT usstanoyevich moderntreatmentmethodsofpatientswithlivermetastasesofcolorectalcancer AT yeidekhissi moderntreatmentmethodsofpatientswithlivermetastasesofcolorectalcancer |