On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States
Objective: Substance use during the COVID-19 (SARS-CoV-2) pandemic has exponentially increased among sexually minoritized men (SMM), who are more vulnerable to COVID-19 transmission, morbidity, and mortality than their heterosexual counterparts. Understanding the factors that mediate and are associa...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Preventive Medicine Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211335525000257 |
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| author | Renessa S. Williams Acklynn M. Byamugisha Leah Davis-Ewart Omar R. Valentin Samantha E. Dilworth Christian Grov Adam W. Carrico |
| author_facet | Renessa S. Williams Acklynn M. Byamugisha Leah Davis-Ewart Omar R. Valentin Samantha E. Dilworth Christian Grov Adam W. Carrico |
| author_sort | Renessa S. Williams |
| collection | DOAJ |
| description | Objective: Substance use during the COVID-19 (SARS-CoV-2) pandemic has exponentially increased among sexually minoritized men (SMM), who are more vulnerable to COVID-19 transmission, morbidity, and mortality than their heterosexual counterparts. Understanding the factors that mediate and are associated with COVID-19 vaccine uptake in a national sample of SMM that use substances may inform targeted interventions to maximize public acceptance. Methods: A cross-sectional analysis was performed using data from a national sample of 2753 SMM in the United States between May 2021–July 2022. We performed a mediation analysis using the Karlson-Holm-Breen method, and factors associated with the likelihood of vaccine uptake were modeled using logistic regression, adjusting for time and age. Results: The median age of the overall sample was 38.9 years old and mainly comprised of White (n = 511; 57 %), HIV-negative (n = 407; 52 %) SMM who used stimulants (n = 724; 92 %). Compared to their counterparts who abstained from drugs in the past three months, SMM who used methamphetamine (aOR: 0.32, CI: 0.24–0.43) or opioids (aOR: 0.52 CI: 0.40–0.67) had significantly lower odds of receiving a COVID-19 vaccine. Those who used cocaine in the past 3 months (aOR: 1.44 CI: 1.20–1.73) had significantly greater odds of receiving a COVID-19 vaccine than those who did not. Vaccine hesitancy partially meditated the direct effects of methamphetamine use on vaccine uptake (OR = 0.40; CI: 0.26–0.61]). Conclusion: The lower vaccination rates among those with a negative HIV status and those who use methamphetamine and opioids warrant attention to inform future vaccination efforts. |
| format | Article |
| id | doaj-art-bd12314799fd4cc6b5d96c588e2da369 |
| institution | Kabale University |
| issn | 2211-3355 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Preventive Medicine Reports |
| spelling | doaj-art-bd12314799fd4cc6b5d96c588e2da3692025-02-08T05:00:20ZengElsevierPreventive Medicine Reports2211-33552025-02-0150102986On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United StatesRenessa S. Williams0Acklynn M. Byamugisha1Leah Davis-Ewart2Omar R. Valentin3Samantha E. Dilworth4Christian Grov5Adam W. Carrico6University of Miami School of Nursing and Health Studies, 5030 Brunson Dr, Miami, FL 33146, USA; Corresponding author.University of Miami Miller School of Medicine Department of Public Health Sciences, 1120 NW 14th St Miami, FL 33136, USAFlorida International University Robert Stempel College of Public Health & Social Work, 11200 SW 8th St Miami, FL 33174, USAFlorida International University Robert Stempel College of Public Health & Social Work, 11200 SW 8th St Miami, FL 33174, USAUniversity of California, San Francisco School of Medicine, 533 Parnassus Ave, San Francisco, CA 94143, USACity University of New York (CUNY) Graduate School of Public Health and Health Policy, Department of Community Health and Social Sciences, 55 W 125th St, New York, NY 10027, USAFlorida International University Robert Stempel College of Public Health & Social Work, 11200 SW 8th St Miami, FL 33174, USAObjective: Substance use during the COVID-19 (SARS-CoV-2) pandemic has exponentially increased among sexually minoritized men (SMM), who are more vulnerable to COVID-19 transmission, morbidity, and mortality than their heterosexual counterparts. Understanding the factors that mediate and are associated with COVID-19 vaccine uptake in a national sample of SMM that use substances may inform targeted interventions to maximize public acceptance. Methods: A cross-sectional analysis was performed using data from a national sample of 2753 SMM in the United States between May 2021–July 2022. We performed a mediation analysis using the Karlson-Holm-Breen method, and factors associated with the likelihood of vaccine uptake were modeled using logistic regression, adjusting for time and age. Results: The median age of the overall sample was 38.9 years old and mainly comprised of White (n = 511; 57 %), HIV-negative (n = 407; 52 %) SMM who used stimulants (n = 724; 92 %). Compared to their counterparts who abstained from drugs in the past three months, SMM who used methamphetamine (aOR: 0.32, CI: 0.24–0.43) or opioids (aOR: 0.52 CI: 0.40–0.67) had significantly lower odds of receiving a COVID-19 vaccine. Those who used cocaine in the past 3 months (aOR: 1.44 CI: 1.20–1.73) had significantly greater odds of receiving a COVID-19 vaccine than those who did not. Vaccine hesitancy partially meditated the direct effects of methamphetamine use on vaccine uptake (OR = 0.40; CI: 0.26–0.61]). Conclusion: The lower vaccination rates among those with a negative HIV status and those who use methamphetamine and opioids warrant attention to inform future vaccination efforts.http://www.sciencedirect.com/science/article/pii/S2211335525000257COVID-19VaccineVaccine hesitancySexual minority menStimulant usePrEP |
| spellingShingle | Renessa S. Williams Acklynn M. Byamugisha Leah Davis-Ewart Omar R. Valentin Samantha E. Dilworth Christian Grov Adam W. Carrico On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States Preventive Medicine Reports COVID-19 Vaccine Vaccine hesitancy Sexual minority men Stimulant use PrEP |
| title | On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States |
| title_full | On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States |
| title_fullStr | On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States |
| title_full_unstemmed | On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States |
| title_short | On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States |
| title_sort | on the fence factors associated with covid 19 vaccine hesitancy among sexually minoritized men who use substances in the united states |
| topic | COVID-19 Vaccine Vaccine hesitancy Sexual minority men Stimulant use PrEP |
| url | http://www.sciencedirect.com/science/article/pii/S2211335525000257 |
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