Iron deficiency anaemia: pathophysiology, assessment, practical management
The WHO has recognised iron deficiency anaemia (IDA) as the most common nutritional deficiency in the world, with 30% of the population being affected with this condition. Although the most common causes of IDA are gastrointestinal bleeding and menstruation in women, decreased dietary iron and decre...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-01-01
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| Series: | BMJ Open Gastroenterology |
| Online Access: | https://bmjopengastro.bmj.com/content/9/1/e000759.full |
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| author | Matthew James Brookes Mark A Samaan Esha Sharma Aditi Kumar Alexandra Marley |
| author_facet | Matthew James Brookes Mark A Samaan Esha Sharma Aditi Kumar Alexandra Marley |
| author_sort | Matthew James Brookes |
| collection | DOAJ |
| description | The WHO has recognised iron deficiency anaemia (IDA) as the most common nutritional deficiency in the world, with 30% of the population being affected with this condition. Although the most common causes of IDA are gastrointestinal bleeding and menstruation in women, decreased dietary iron and decreased iron absorption are also culpable causes. Patients with IDA should be treated with the aim of replenishing iron stores and returning the haemoglobin to a normal level. This has shown to improve quality of life, morbidity, prognosis in chronic disease and outcomes in pregnancy. Iron deficiency occurs in many chronic inflammatory conditions, including congestive cardiac failure, chronic kidney disease and inflammatory bowel disease. This article will provide an updated overview on diagnosis and management of IDA in patients with chronic conditions, preoperative and in pregnancy. We will discuss the benefits and limitations of oral versus intravenous iron replacement in each cohort, with an overview on cost analysis between the different iron formulations currently on the market. |
| format | Article |
| id | doaj-art-be36eddf923f421c9ad7a4b38ceb32a6 |
| institution | Kabale University |
| issn | 2054-4774 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Gastroenterology |
| spelling | doaj-art-be36eddf923f421c9ad7a4b38ceb32a62025-02-07T14:05:28ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742022-01-019110.1136/bmjgast-2021-000759Iron deficiency anaemia: pathophysiology, assessment, practical managementMatthew James Brookes0Mark A Samaan1Esha Sharma2Aditi Kumar3Alexandra Marley4Research Institue, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton, UK7 Department of Gastroenterology, Guy`s and Saint Thomas` Hospitals NHS Trust, London, UKIBD Centre, Guy`s and St Thomas` NHS Foundation Trust, London, UK1 Department of Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UKDepartment of Gastroenterology, The Royal Wolverhampton NHS Trust, Wolverhampton, UKThe WHO has recognised iron deficiency anaemia (IDA) as the most common nutritional deficiency in the world, with 30% of the population being affected with this condition. Although the most common causes of IDA are gastrointestinal bleeding and menstruation in women, decreased dietary iron and decreased iron absorption are also culpable causes. Patients with IDA should be treated with the aim of replenishing iron stores and returning the haemoglobin to a normal level. This has shown to improve quality of life, morbidity, prognosis in chronic disease and outcomes in pregnancy. Iron deficiency occurs in many chronic inflammatory conditions, including congestive cardiac failure, chronic kidney disease and inflammatory bowel disease. This article will provide an updated overview on diagnosis and management of IDA in patients with chronic conditions, preoperative and in pregnancy. We will discuss the benefits and limitations of oral versus intravenous iron replacement in each cohort, with an overview on cost analysis between the different iron formulations currently on the market.https://bmjopengastro.bmj.com/content/9/1/e000759.full |
| spellingShingle | Matthew James Brookes Mark A Samaan Esha Sharma Aditi Kumar Alexandra Marley Iron deficiency anaemia: pathophysiology, assessment, practical management BMJ Open Gastroenterology |
| title | Iron deficiency anaemia: pathophysiology, assessment, practical management |
| title_full | Iron deficiency anaemia: pathophysiology, assessment, practical management |
| title_fullStr | Iron deficiency anaemia: pathophysiology, assessment, practical management |
| title_full_unstemmed | Iron deficiency anaemia: pathophysiology, assessment, practical management |
| title_short | Iron deficiency anaemia: pathophysiology, assessment, practical management |
| title_sort | iron deficiency anaemia pathophysiology assessment practical management |
| url | https://bmjopengastro.bmj.com/content/9/1/e000759.full |
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