Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China
Abstract Many epidemiological studies focus on health research in areas with high concentration of PM2.5. To fill the research gap, our study investigated the acute effects of low PM2.5 level (annual average concentration below 35 µg m−3) on asthma admissions in Xiamen, China. Using a time-stratifie...
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| Format: | Article |
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Springer
2023-12-01
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| Series: | Aerosol and Air Quality Research |
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| Online Access: | https://doi.org/10.4209/aaqr.230195 |
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| author | Xiaolong Fan Chen Yang Jinsheng Chen Yuping Chen Gaojie Chen Ziyi Lin Zecong Li Yanting Chen Liqian Yin Lingling Xu Naian Xiao |
| author_facet | Xiaolong Fan Chen Yang Jinsheng Chen Yuping Chen Gaojie Chen Ziyi Lin Zecong Li Yanting Chen Liqian Yin Lingling Xu Naian Xiao |
| author_sort | Xiaolong Fan |
| collection | DOAJ |
| description | Abstract Many epidemiological studies focus on health research in areas with high concentration of PM2.5. To fill the research gap, our study investigated the acute effects of low PM2.5 level (annual average concentration below 35 µg m−3) on asthma admissions in Xiamen, China. Using a time-stratified case-crossover study design, we examined the association between PM2.5 concentration and asthma admissions from January 2019 to November 2021. The results showed a positive correlation between PM2.5 concentration and the cumulative incidence of asthma, with a lag of 0–7 days. Each 10 µg m−3 increased in PM2.5 concentration was associated with a 0.49% increase in asthma incidence. Stratified analysis revealed significant effects in children aged 0–4 years (OR = 2.029, 95% CI = 1.359–3.031) and the elderly population aged over 75 years (OR = 1.399, 95% CI = 1.092–1.793). Distributed lag models demonstrated a hysteresis effect, with significant lagged effects observed in children (lag0–5) and the elderly (lag3–lag5). The multi-pollutant model, considering NO2 and O3, showed consistent results. These findings highlight the age-specific susceptibility to PM2.5 exposure and its impact on asthma admissions, even at lower levels of pollution. Further research is needed to inform environmental protection policies and public health interventions in low-pollution environments. |
| format | Article |
| id | doaj-art-bfe55ea18a5f4f5295067c1e8c21ec8d |
| institution | Kabale University |
| issn | 1680-8584 2071-1409 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Springer |
| record_format | Article |
| series | Aerosol and Air Quality Research |
| spelling | doaj-art-bfe55ea18a5f4f5295067c1e8c21ec8d2025-02-09T12:24:42ZengSpringerAerosol and Air Quality Research1680-85842071-14092023-12-0124211110.4209/aaqr.230195Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in ChinaXiaolong Fan0Chen Yang1Jinsheng Chen2Yuping Chen3Gaojie Chen4Ziyi Lin5Zecong Li6Yanting Chen7Liqian Yin8Lingling Xu9Naian Xiao10Center for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesFujian Key Laboratory of Atmospheric Ozone Pollution Prevention, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesCenter for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of SciencesDepartment of Neurology, The Third Hospital of XiamenAbstract Many epidemiological studies focus on health research in areas with high concentration of PM2.5. To fill the research gap, our study investigated the acute effects of low PM2.5 level (annual average concentration below 35 µg m−3) on asthma admissions in Xiamen, China. Using a time-stratified case-crossover study design, we examined the association between PM2.5 concentration and asthma admissions from January 2019 to November 2021. The results showed a positive correlation between PM2.5 concentration and the cumulative incidence of asthma, with a lag of 0–7 days. Each 10 µg m−3 increased in PM2.5 concentration was associated with a 0.49% increase in asthma incidence. Stratified analysis revealed significant effects in children aged 0–4 years (OR = 2.029, 95% CI = 1.359–3.031) and the elderly population aged over 75 years (OR = 1.399, 95% CI = 1.092–1.793). Distributed lag models demonstrated a hysteresis effect, with significant lagged effects observed in children (lag0–5) and the elderly (lag3–lag5). The multi-pollutant model, considering NO2 and O3, showed consistent results. These findings highlight the age-specific susceptibility to PM2.5 exposure and its impact on asthma admissions, even at lower levels of pollution. Further research is needed to inform environmental protection policies and public health interventions in low-pollution environments.https://doi.org/10.4209/aaqr.230195PM2.5Asthma hospitalizationHealth risks Time-stratified |
| spellingShingle | Xiaolong Fan Chen Yang Jinsheng Chen Yuping Chen Gaojie Chen Ziyi Lin Zecong Li Yanting Chen Liqian Yin Lingling Xu Naian Xiao Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China Aerosol and Air Quality Research PM2.5 Asthma hospitalization Health risks Time-stratified |
| title | Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China |
| title_full | Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China |
| title_fullStr | Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China |
| title_full_unstemmed | Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China |
| title_short | Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China |
| title_sort | impact of low pm2 5 exposure on asthma admission age specific differences and evidence from a low pollution environment in china |
| topic | PM2.5 Asthma hospitalization Health risks Time-stratified |
| url | https://doi.org/10.4209/aaqr.230195 |
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