A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic Pain
# Purpose of Review Chronic pain continues to be one of the leading healthcare cost burdens in the United States and is typically defined as ongoing pain, lasting longer than six months. Various treatment options exist for chronic pain, including physical therapy, medical management, pain psycholog...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Open Medical Publishing
2022-05-01
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| Series: | Health Psychology Research |
| Online Access: | https://doi.org/10.52965/001c.32309 |
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| author | Christopher Robinson Suhani Dalal Ahish Chitneni Anand Patil Amnon A. Berger Syed Mahmood Vwaire Orhurhu Alan D. Kaye Jamal Hasoon |
| author_facet | Christopher Robinson Suhani Dalal Ahish Chitneni Anand Patil Amnon A. Berger Syed Mahmood Vwaire Orhurhu Alan D. Kaye Jamal Hasoon |
| author_sort | Christopher Robinson |
| collection | DOAJ |
| description | # Purpose of Review
Chronic pain continues to be one of the leading healthcare cost burdens in the United States and is typically defined as ongoing pain, lasting longer than six months. Various treatment options exist for chronic pain, including physical therapy, medical management, pain psychology, and interventional therapies. Pain medications have been the mainstay of treatment for chronic pain conditions with an increasing use of membrane stabilizers and antidepressants to treat neuropathic pain conditions. Specifically, serotonin noradrenaline reuptake inhibitors (SNRIs) have been used to treat a range of pain conditions expanding from everyday use for depressive disorders.
# Recent Findings
SNRIs, including duloxetine, venlafaxine, and milnacipran, have demonstrated efficacy in reducing pain in musculoskeletal pain (chronic low back pain and osteoarthritis), fibromyalgia, and neuropathic pain conditions (peripheral diabetic neuropathy).
# Summary
The article describes the function, role, and use of SNRIs to treat chronic and neuropathic pain by altering the noradrenergic descending inhibitory pathways. |
| format | Article |
| id | doaj-art-c45b4133635e4d1dbd1409a858ec6922 |
| institution | Kabale University |
| issn | 2420-8124 |
| language | English |
| publishDate | 2022-05-01 |
| publisher | Open Medical Publishing |
| record_format | Article |
| series | Health Psychology Research |
| spelling | doaj-art-c45b4133635e4d1dbd1409a858ec69222025-02-11T20:30:34ZengOpen Medical PublishingHealth Psychology Research2420-81242022-05-01102A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic PainChristopher RobinsonSuhani DalalAhish ChitneniAnand PatilAmnon A. BergerSyed MahmoodVwaire OrhurhuAlan D. KayeJamal Hasoon# Purpose of Review Chronic pain continues to be one of the leading healthcare cost burdens in the United States and is typically defined as ongoing pain, lasting longer than six months. Various treatment options exist for chronic pain, including physical therapy, medical management, pain psychology, and interventional therapies. Pain medications have been the mainstay of treatment for chronic pain conditions with an increasing use of membrane stabilizers and antidepressants to treat neuropathic pain conditions. Specifically, serotonin noradrenaline reuptake inhibitors (SNRIs) have been used to treat a range of pain conditions expanding from everyday use for depressive disorders. # Recent Findings SNRIs, including duloxetine, venlafaxine, and milnacipran, have demonstrated efficacy in reducing pain in musculoskeletal pain (chronic low back pain and osteoarthritis), fibromyalgia, and neuropathic pain conditions (peripheral diabetic neuropathy). # Summary The article describes the function, role, and use of SNRIs to treat chronic and neuropathic pain by altering the noradrenergic descending inhibitory pathways.https://doi.org/10.52965/001c.32309 |
| spellingShingle | Christopher Robinson Suhani Dalal Ahish Chitneni Anand Patil Amnon A. Berger Syed Mahmood Vwaire Orhurhu Alan D. Kaye Jamal Hasoon A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic Pain Health Psychology Research |
| title | A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic Pain |
| title_full | A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic Pain |
| title_fullStr | A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic Pain |
| title_full_unstemmed | A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic Pain |
| title_short | A Look at Commonly Utilized Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in Chronic Pain |
| title_sort | look at commonly utilized serotonin noradrenaline reuptake inhibitors snris in chronic pain |
| url | https://doi.org/10.52965/001c.32309 |
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