Prospective observational study of oral clonazepam to prevent high-dose busulfan-induced seizures in adult patients

Abstract Background Busulfan at high doses has been associated with a risk of seizures. Phenytoin has been used traditionally as anti-seizure prophylaxis, and benzodiazepines and levetiracetam have been introduced more recently, providing data from retrospective series. The main purpose of this stud...

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Main Authors: María Sacramento Díaz-Carrasco, Andrés Sánchez-Salinas, Juan José Fernández-Ávila, Raquel Olmos-Jiménez, Ignacio Español-Morales, Alberto Espuny-Miró
Format: Article
Language:English
Published: SpringerOpen 2025-02-01
Series:Journal of the Egyptian National Cancer Institute
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Online Access:https://doi.org/10.1186/s43046-025-00257-3
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