Molecular response to multiple trace element contamination of the European sardine
In marine ecosystems, the presence of trace elements resulting from anthropogenic activities has raised concerns regarding their potential effects on marine organisms. This study delves into the intricate relationship between trace element contamination and the physiological responses of a key marin...
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2024-08-01
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| Online Access: | https://peercommunityjournal.org/articles/10.24072/pcjournal.450/ |
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| author | Beauvieux, Anaïs Fromentin, Jean-Marc Saraux, Claire Romero, Diego Couffin, Nathan Brown, Adrien Metral, Luisa Bertile, Fabrice Schull, Quentin |
| author_facet | Beauvieux, Anaïs Fromentin, Jean-Marc Saraux, Claire Romero, Diego Couffin, Nathan Brown, Adrien Metral, Luisa Bertile, Fabrice Schull, Quentin |
| author_sort | Beauvieux, Anaïs |
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| description | In marine ecosystems, the presence of trace elements resulting from anthropogenic activities has raised concerns regarding their potential effects on marine organisms. This study delves into the intricate relationship between trace element contamination and the physiological responses of a key marine species in the Mediterranean Sea: the European sardine. Since 2008, this species has been experiencing a significant crisis in the region, prompting numerous studies to investigate the potential factors behind the dramatic decline in sardines size, age, and body condition. However, thorough information on chemical contamination by trace elements and its physiological impact on this species was lacking. We found evidence for the accumulation of multiple elements in sardines, with a light East-West contamination gradient within the Gulf of Lions. While macro-physiological parameters (i.e. body condition) were not affected by contamination, pathways involved in cellular organization and response to stress were clearly upregulated, particularly in the liver, but also in muscle. In addition, a global upregulation in processes linked to the immune system, lipid homeostasis and oxidative stress was recorded in the liver. The associated energetic cost may add a substantial burden to sardines that already face multi-factorial constraints. This study also allows to pinpoint biomarkers of exposure and effects that may be important for monitoring Mediterranean sardine health. The results of this study and particularly the complex changes in protein expression demonstrate the need for future studies to test the concomitant effects of multiple stressors acting simultaneously, including large scale contamination. |
| format | Article |
| id | doaj-art-c59fc5ace9734d3e929cb06561446c82 |
| institution | Kabale University |
| issn | 2804-3871 |
| language | English |
| publishDate | 2024-08-01 |
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| spelling | doaj-art-c59fc5ace9734d3e929cb06561446c822025-02-07T10:17:18ZengPeer Community InPeer Community Journal2804-38712024-08-01410.24072/pcjournal.45010.24072/pcjournal.450Molecular response to multiple trace element contamination of the European sardine Beauvieux, Anaïs0https://orcid.org/0009-0002-2472-4057Fromentin, Jean-Marc1https://orcid.org/0000-0002-1496-4332Saraux, Claire2https://orcid.org/0000-0001-5061-4009Romero, Diego3Couffin, Nathan4Brown, Adrien5Metral, Luisa6Bertile, Fabrice7https://orcid.org/0000-0001-5510-4868Schull, Quentin8https://orcid.org/0000-0001-9297-3376MARBEC, Univ Montpellier, CNRS, Ifremer, IRD, Sète, FranceMARBEC, Univ Montpellier, CNRS, Ifremer, IRD, Sète, FranceUniversité de Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, FranceToxicology Department, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, SpainUniversité de Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, France; Infrastructure Nationale de Protéomique ProFI, FR2048 CNRS CEA, Strasbourg 67087, FranceUniversité de Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, France; Infrastructure Nationale de Protéomique ProFI, FR2048 CNRS CEA, Strasbourg 67087, FranceMARBEC, Univ Montpellier, CNRS, Ifremer, IRD, Sète, FranceUniversité de Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, France; Infrastructure Nationale de Protéomique ProFI, FR2048 CNRS CEA, Strasbourg 67087, FranceMARBEC, Univ Montpellier, CNRS, Ifremer, IRD, Sète, FranceIn marine ecosystems, the presence of trace elements resulting from anthropogenic activities has raised concerns regarding their potential effects on marine organisms. This study delves into the intricate relationship between trace element contamination and the physiological responses of a key marine species in the Mediterranean Sea: the European sardine. Since 2008, this species has been experiencing a significant crisis in the region, prompting numerous studies to investigate the potential factors behind the dramatic decline in sardines size, age, and body condition. However, thorough information on chemical contamination by trace elements and its physiological impact on this species was lacking. We found evidence for the accumulation of multiple elements in sardines, with a light East-West contamination gradient within the Gulf of Lions. While macro-physiological parameters (i.e. body condition) were not affected by contamination, pathways involved in cellular organization and response to stress were clearly upregulated, particularly in the liver, but also in muscle. In addition, a global upregulation in processes linked to the immune system, lipid homeostasis and oxidative stress was recorded in the liver. The associated energetic cost may add a substantial burden to sardines that already face multi-factorial constraints. This study also allows to pinpoint biomarkers of exposure and effects that may be important for monitoring Mediterranean sardine health. The results of this study and particularly the complex changes in protein expression demonstrate the need for future studies to test the concomitant effects of multiple stressors acting simultaneously, including large scale contamination.https://peercommunityjournal.org/articles/10.24072/pcjournal.450/Cocktail effectEcotoxicologyGulf of LionsSardina pilchardusShotgun proteomic |
| spellingShingle | Beauvieux, Anaïs Fromentin, Jean-Marc Saraux, Claire Romero, Diego Couffin, Nathan Brown, Adrien Metral, Luisa Bertile, Fabrice Schull, Quentin Molecular response to multiple trace element contamination of the European sardine Peer Community Journal Cocktail effect Ecotoxicology Gulf of Lions Sardina pilchardus Shotgun proteomic |
| title | Molecular response to multiple trace element contamination of the European sardine
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| title_full | Molecular response to multiple trace element contamination of the European sardine
|
| title_fullStr | Molecular response to multiple trace element contamination of the European sardine
|
| title_full_unstemmed | Molecular response to multiple trace element contamination of the European sardine
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| title_short | Molecular response to multiple trace element contamination of the European sardine
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| title_sort | molecular response to multiple trace element contamination of the european sardine |
| topic | Cocktail effect Ecotoxicology Gulf of Lions Sardina pilchardus Shotgun proteomic |
| url | https://peercommunityjournal.org/articles/10.24072/pcjournal.450/ |
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