TDP-43 as a potential retinal biomarker for neurodegenerative diseases

TDP-43 as a potential retinal biomarker for neurodegenerative diseases

TDP-43 proteinopathies are a spectrum of neurodegenerative diseases (NDDs) characterized by the pathological cytoplasmic aggregation of the TDP-43 protein. These include amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), Alzheimer’s disease (AD), chronic traumatic encepha...

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Bibliographic Details
Main Authors: Margit Glashutter, Printha Wijesinghe, Joanne A. Matsubara
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Neuroscience
Subjects:
TDP-43 proteinopathy
neurodegenerative disease
biomarker
retina
eye
brain
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1533045/full
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