Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine

Roger Guillemin discovered and characterized the hypothalamic factors that control anterior pituitary functions. He consequently demonstrated that these brain peptides regulate a large number of major body activities through neuroendocrine mechanisms. This especially include growth, fertility and re...

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Main Authors: Mougin, Christiane, Rossier, Jean, Bloch, Bertrand
Format: Article
Language:English
Published: Académie des sciences 2024-08-01
Series:Comptes Rendus Biologies
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Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.156/
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author Mougin, Christiane
Rossier, Jean
Bloch, Bertrand
author_facet Mougin, Christiane
Rossier, Jean
Bloch, Bertrand
author_sort Mougin, Christiane
collection DOAJ
description Roger Guillemin discovered and characterized the hypothalamic factors that control anterior pituitary functions. He consequently demonstrated that these brain peptides regulate a large number of major body activities through neuroendocrine mechanisms. This especially include growth, fertility and reproduction, endocrine gland functions and stress. These seminal works paved the way to major applications in many fields of physiology and medicine for diagnosis, pharmacology and therapy, far beyond the initial discovery and properties of these molecules, including in cancerology, immunology, inflammation, drug addiction and behavior.
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spelling doaj-art-c8b0f778bfce448e9ff5c1e2e6d8c1022025-02-07T10:37:47ZengAcadémie des sciencesComptes Rendus Biologies1768-32382024-08-01347G1535810.5802/crbiol.15610.5802/crbiol.156Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or MedicineMougin, Christiane0Rossier, Jean1https://orcid.org/0000-0003-1821-2135Bloch, Bertrand2https://orcid.org/0009-0007-5404-7989Department of Cellular Biology, University of Franche-Comté, FranceAcademy of Sciences, Institut de France, France; Royal Academy of Medicine, BelgiumUniversity of Bordeaux, FranceRoger Guillemin discovered and characterized the hypothalamic factors that control anterior pituitary functions. He consequently demonstrated that these brain peptides regulate a large number of major body activities through neuroendocrine mechanisms. This especially include growth, fertility and reproduction, endocrine gland functions and stress. These seminal works paved the way to major applications in many fields of physiology and medicine for diagnosis, pharmacology and therapy, far beyond the initial discovery and properties of these molecules, including in cancerology, immunology, inflammation, drug addiction and behavior.https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.156/NeuroendocrinologyReleasing factorsHypothalamusAnterior pituitaryEndorphins
spellingShingle Mougin, Christiane
Rossier, Jean
Bloch, Bertrand
Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine
Comptes Rendus Biologies
Neuroendocrinology
Releasing factors
Hypothalamus
Anterior pituitary
Endorphins
title Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine
title_full Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine
title_fullStr Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine
title_full_unstemmed Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine
title_short Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine
title_sort tribute to roger guillemin a pioneer in neuroendocrinology 1924 2024 nobel prize in physiology or medicine
topic Neuroendocrinology
Releasing factors
Hypothalamus
Anterior pituitary
Endorphins
url https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.156/
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