Anopheles gambiae phagocytic hemocytes promote Plasmodium falciparum infection by regulating midgut epithelial integrity

Abstract For successful transmission, the malaria parasite must traverse tissue epithelia and survive attack from the insect’s innate immune system. Hemocytes play a multitude of roles in mosquitoes, including defense against invading pathogens. Here, we show that hemocytes of the major malaria vect...

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Bibliographic Details
Main Authors: Victor Cardoso-Jaime, George Dimopoulos
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56313-y
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