Diffusion-programmed catalysis in nanoporous material
Abstract In the realm of heterogeneous catalysis, the diffusion of reactants into catalytically active sites stands as a pivotal determinant influencing both turnover frequency and geometric selectivity in product formation. While accelerated diffusion of reactants can elevate reaction rates, it oft...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-56575-6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823861842928205824 |
|---|---|
| author | Suvendu Panda Tanmoy Maity Susmita Sarkar Arun Kumar Manna Jagannath Mondal Ritesh Haldar |
| author_facet | Suvendu Panda Tanmoy Maity Susmita Sarkar Arun Kumar Manna Jagannath Mondal Ritesh Haldar |
| author_sort | Suvendu Panda |
| collection | DOAJ |
| description | Abstract In the realm of heterogeneous catalysis, the diffusion of reactants into catalytically active sites stands as a pivotal determinant influencing both turnover frequency and geometric selectivity in product formation. While accelerated diffusion of reactants can elevate reaction rates, it often entails a compromise in geometric selectivity. Porous catalysts, including metal-organic and covalent organic frameworks, confront formidable obstacles in regulating reactant diffusion rates. Consequently, the chemical functionality of the catalysts typically governs turnover frequency and geometric selectivity. This study presents an approach harnessing diffusion length to achieve improved selectivity and manipulation of reactant-active site residence time at active sites to augment reaction kinetics. Through the deployment of a thin film composed of a porous metal-organic framework catalyst, we illustrate how programming reactant diffusion within a cross-flow microfluidic catalytic reactor can concurrently amplify turnover frequency (exceeding 1000-fold) and enhance geometric selectivity ( ~ 2-fold) relative to conventional nano/microcrystals of catalyst in one-pot reactor. This diffusion-programed strategy represents a robust solution to surmount the constraints imposed by bulk nano/microcrystals of catalysts, marking advancement in the design of porous catalyst-driven organic reactions. |
| format | Article |
| id | doaj-art-c9b3239b0d8d4bcbb542adae17238d95 |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-c9b3239b0d8d4bcbb542adae17238d952025-02-09T12:44:27ZengNature PortfolioNature Communications2041-17232025-02-011611810.1038/s41467-025-56575-6Diffusion-programmed catalysis in nanoporous materialSuvendu Panda0Tanmoy Maity1Susmita Sarkar2Arun Kumar Manna3Jagannath Mondal4Ritesh Haldar5Tata Institute of Fundamental Research HyderabadTata Institute of Fundamental Research HyderabadTata Institute of Fundamental Research HyderabadTata Institute of Fundamental Research HyderabadTata Institute of Fundamental Research HyderabadTata Institute of Fundamental Research HyderabadAbstract In the realm of heterogeneous catalysis, the diffusion of reactants into catalytically active sites stands as a pivotal determinant influencing both turnover frequency and geometric selectivity in product formation. While accelerated diffusion of reactants can elevate reaction rates, it often entails a compromise in geometric selectivity. Porous catalysts, including metal-organic and covalent organic frameworks, confront formidable obstacles in regulating reactant diffusion rates. Consequently, the chemical functionality of the catalysts typically governs turnover frequency and geometric selectivity. This study presents an approach harnessing diffusion length to achieve improved selectivity and manipulation of reactant-active site residence time at active sites to augment reaction kinetics. Through the deployment of a thin film composed of a porous metal-organic framework catalyst, we illustrate how programming reactant diffusion within a cross-flow microfluidic catalytic reactor can concurrently amplify turnover frequency (exceeding 1000-fold) and enhance geometric selectivity ( ~ 2-fold) relative to conventional nano/microcrystals of catalyst in one-pot reactor. This diffusion-programed strategy represents a robust solution to surmount the constraints imposed by bulk nano/microcrystals of catalysts, marking advancement in the design of porous catalyst-driven organic reactions.https://doi.org/10.1038/s41467-025-56575-6 |
| spellingShingle | Suvendu Panda Tanmoy Maity Susmita Sarkar Arun Kumar Manna Jagannath Mondal Ritesh Haldar Diffusion-programmed catalysis in nanoporous material Nature Communications |
| title | Diffusion-programmed catalysis in nanoporous material |
| title_full | Diffusion-programmed catalysis in nanoporous material |
| title_fullStr | Diffusion-programmed catalysis in nanoporous material |
| title_full_unstemmed | Diffusion-programmed catalysis in nanoporous material |
| title_short | Diffusion-programmed catalysis in nanoporous material |
| title_sort | diffusion programmed catalysis in nanoporous material |
| url | https://doi.org/10.1038/s41467-025-56575-6 |
| work_keys_str_mv | AT suvendupanda diffusionprogrammedcatalysisinnanoporousmaterial AT tanmoymaity diffusionprogrammedcatalysisinnanoporousmaterial AT susmitasarkar diffusionprogrammedcatalysisinnanoporousmaterial AT arunkumarmanna diffusionprogrammedcatalysisinnanoporousmaterial AT jagannathmondal diffusionprogrammedcatalysisinnanoporousmaterial AT riteshhaldar diffusionprogrammedcatalysisinnanoporousmaterial |