Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019

Abstract Background To investigate the global, regional, and national burden of the diseases attributable to excess body weight (EBW) from 1990 to 2019, stratified by age, sex, underlying cause, and sociodemographic index (SDI). Methods Using the Comparative Risk Assessment approach of the Global Bu...

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Main Authors: Saeid Safiri, Jessica A. Grieger, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Asra Fazlollahi, Mark J. M. Sullman, Nahid Karamzad, Fikrettin Sahin, Kuljit Singh, Gary S. Collins, Ali-Asghar Kolahi
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Nutrition Journal
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Online Access:https://doi.org/10.1186/s12937-025-01082-z
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author Saeid Safiri
Jessica A. Grieger
Amir Ghaffari Jolfayi
Seyed Ehsan Mousavi
Seyed Aria Nejadghaderi
Asra Fazlollahi
Mark J. M. Sullman
Nahid Karamzad
Fikrettin Sahin
Kuljit Singh
Gary S. Collins
Ali-Asghar Kolahi
author_facet Saeid Safiri
Jessica A. Grieger
Amir Ghaffari Jolfayi
Seyed Ehsan Mousavi
Seyed Aria Nejadghaderi
Asra Fazlollahi
Mark J. M. Sullman
Nahid Karamzad
Fikrettin Sahin
Kuljit Singh
Gary S. Collins
Ali-Asghar Kolahi
author_sort Saeid Safiri
collection DOAJ
description Abstract Background To investigate the global, regional, and national burden of the diseases attributable to excess body weight (EBW) from 1990 to 2019, stratified by age, sex, underlying cause, and sociodemographic index (SDI). Methods Using the Comparative Risk Assessment approach of the Global Burden of Disease (GBD) study 2019, the burden of diseases attributable to EBW was reported for the period from 1990 to 2019. For adults, EBW was defined as a body mass index (BMI) exceeding 25 kg/m2, while for children aged 1 to 19 years, EBW was determined according to the standards set by the International Obesity Taskforce. The burden was reported in terms of numbers, proportions, and age-standardised rates per 100,000, accompanied by corresponding 95% uncertainty intervals (UIs). Results In 2019, there were an estimated 5.0 million deaths (95% UI: 3.2–7.1) and 160.3 million DALYs (106.0–218.9) attributable to EBW worldwide. The age-standardised DALY rate attributable to EBW increased by 18.0% (2.2–42.3) from 1990 to 2019, with notable regional variations. Southeast Asia and South Asia exhibited the highest age-standardised DALY rates. Conversely, the age-standardised death rate due to EBW showed no significant change, with an increase of 4.9% (-7.3 to 24.6) over the same period. Significant regional variations were again observed, particularly in Southeast Asia and South Asia, which recorded the highest age-standardised death rates. Moreover, a non-linear association was observed between the SDI and the regional age-standardised DALY rate of diseases attributable to EBW. Conclusions The global burden of EBW has increased over the past three decades. This trend aligns with socio-demographic indices and is influenced by the physical activity levels and dietary habits of these populations.
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spelling doaj-art-ca3de6399e654f3d9a55f76ca0cf3c9f2025-02-09T12:13:41ZengBMCNutrition Journal1475-28912025-02-0124111410.1186/s12937-025-01082-zBurden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019Saeid Safiri0Jessica A. Grieger1Amir Ghaffari Jolfayi2Seyed Ehsan Mousavi3Seyed Aria Nejadghaderi4Asra Fazlollahi5Mark J. M. Sullman6Nahid Karamzad7Fikrettin Sahin8Kuljit Singh9Gary S. Collins10Ali-Asghar Kolahi11Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical SciencesAdelaide Medical School, University of AdelaideCardiovascular Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical SciencesNeurosciences Research Center, Aging Research Institute, Tabriz University of Medical SciencesHIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical SciencesSocial Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical SciencesDepartment of Life and Health Sciences, University of NicosiaDepartment of Persian Medicine, Tabriz University of Medical SciencesDepartment of Genetics and Bioengineering, Yeditepe UniversityDepartment of Medicine, Griffith UniversityCentre for Statistics in Medicine, NDORMS, Botnar Research Centre, University of OxfordSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesAbstract Background To investigate the global, regional, and national burden of the diseases attributable to excess body weight (EBW) from 1990 to 2019, stratified by age, sex, underlying cause, and sociodemographic index (SDI). Methods Using the Comparative Risk Assessment approach of the Global Burden of Disease (GBD) study 2019, the burden of diseases attributable to EBW was reported for the period from 1990 to 2019. For adults, EBW was defined as a body mass index (BMI) exceeding 25 kg/m2, while for children aged 1 to 19 years, EBW was determined according to the standards set by the International Obesity Taskforce. The burden was reported in terms of numbers, proportions, and age-standardised rates per 100,000, accompanied by corresponding 95% uncertainty intervals (UIs). Results In 2019, there were an estimated 5.0 million deaths (95% UI: 3.2–7.1) and 160.3 million DALYs (106.0–218.9) attributable to EBW worldwide. The age-standardised DALY rate attributable to EBW increased by 18.0% (2.2–42.3) from 1990 to 2019, with notable regional variations. Southeast Asia and South Asia exhibited the highest age-standardised DALY rates. Conversely, the age-standardised death rate due to EBW showed no significant change, with an increase of 4.9% (-7.3 to 24.6) over the same period. Significant regional variations were again observed, particularly in Southeast Asia and South Asia, which recorded the highest age-standardised death rates. Moreover, a non-linear association was observed between the SDI and the regional age-standardised DALY rate of diseases attributable to EBW. Conclusions The global burden of EBW has increased over the past three decades. This trend aligns with socio-demographic indices and is influenced by the physical activity levels and dietary habits of these populations.https://doi.org/10.1186/s12937-025-01082-zObesityOverweightDeathMortalityPrevalenceIncidence
spellingShingle Saeid Safiri
Jessica A. Grieger
Amir Ghaffari Jolfayi
Seyed Ehsan Mousavi
Seyed Aria Nejadghaderi
Asra Fazlollahi
Mark J. M. Sullman
Nahid Karamzad
Fikrettin Sahin
Kuljit Singh
Gary S. Collins
Ali-Asghar Kolahi
Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019
Nutrition Journal
Obesity
Overweight
Death
Mortality
Prevalence
Incidence
title Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019
title_full Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019
title_fullStr Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019
title_full_unstemmed Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019
title_short Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019
title_sort burden of diseases attributable to excess body weight in 204 countries and territories 1990 2019
topic Obesity
Overweight
Death
Mortality
Prevalence
Incidence
url https://doi.org/10.1186/s12937-025-01082-z
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