Plasma from hypertensive pregnancy patients induce endothelial dysfunction even under atheroprotective shear stress

Plasma from hypertensive pregnancy patients induce endothelial dysfunction even under atheroprotective shear stress

Abstract Preeclampsia (PE) is a challenge in maternal healthcare due to its complex nature, characterized by high blood pressure, protein in the urine, and damage to various organs. There is evidence linking PE to endothelial dysfunction (ED), triggered by substances released from an oxygen-deprived...

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Bibliographic Details
Main Authors: Sarah Viana-Mattioli, Miriam Helena Fonseca-Alaniz, Iguaracy Pinheiro-de-Sousa, Ricardo Rosa Junior, Moises Henrique Mastella, Ricardo de Carvalho Cavalli, Valeria Cristina Sandrim
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Endothelial dysfunction
Pregnancy
Hypertension
Shear stress
Preeclampsia
Online Access:https://doi.org/10.1038/s41598-025-88902-8
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