Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation Syndrome
OBJECTIVE: The purpose of the present study is to compare the use of GnRH antagonist salvage versus coasting for the prevention of OHSS in patients undergoing IVF/ICSI cycles with long GnRH agonist protocol. STUDY DESIGN: Medical records of 91 patients (41 in coasting and 49 in GnRH antagonist grou...
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| Format: | Article |
| Language: | English |
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Medical Network
2013-12-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/213 |
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| _version_ | 1823857379353034752 |
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| author | Cavidan Gülerman Nafiye Yılmaz Ayla Sargın Oruç Nazlı Özkan Ayten Türkkanı Esma Sarıkaya Okan Yenicesu |
| author_facet | Cavidan Gülerman Nafiye Yılmaz Ayla Sargın Oruç Nazlı Özkan Ayten Türkkanı Esma Sarıkaya Okan Yenicesu |
| author_sort | Cavidan Gülerman |
| collection | DOAJ |
| description |
OBJECTIVE: The purpose of the present study is to compare the use of GnRH antagonist salvage versus coasting for the prevention of OHSS in patients undergoing IVF/ICSI cycles with long GnRH agonist protocol.
STUDY DESIGN: Medical records of 91 patients (41 in coasting and 49 in GnRH antagonist group) identified as at high risk of developing OHSS were reviewed retrospectively. Groups were compared for occurrence of moderate and severe OHSS, serum estradiol on the day of HCG and IVF outcomes.
RESULTS: There were no differences between the groups in terms of moderate and severe OHSS and clinical pregnancy rates. Serum estradiol levels were decreased significantly in GnRH antagonist group. Quality of the transferred embryos was better in the coasting group.
CONCLUSION: Our results represent that both coasting and GnRH antagonist salvage are effective strategies to prevent OHSS in women undergoing long GnRH agonist IVF/ICSI cycles.
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| format | Article |
| id | doaj-art-cb0975d16b104e40bb716a0d39a37b02 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2013-12-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-cb0975d16b104e40bb716a0d39a37b022025-02-11T21:22:13ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182013-12-01193151Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation SyndromeCavidan Gülerman0Nafiye Yılmaz1Ayla Sargın Oruç2Nazlı Özkan3Ayten Türkkanı4Esma Sarıkaya5Okan Yenicesu6Zekai Tahir Burak Women’s Health Education and Research Hospital Department of Reproductive Endocrinology, AnkaraZekai Tahir Burak Women’s Health Education and Research Hospital Department of Reproductive Endocrinology, AnkaraZekai Tahir Burak Women’s Health Education and Research Hospital Department of Reproductive Endocrinology, AnkaraZekai Tahir Burak Women’s Health Education and Research Hospital Department of Reproductive Endocrinology, AnkaraZekai Tahir Burak Women’s Health Education and Research Hospital Department of Reproductive Endocrinology, AnkaraZekai Tahir Burak Women’s Health Education and Research Hospital Department of Reproductive Endocrinology, AnkaraZekai Tahir Burak Women’s Health Education and Research Hospital Department of Reproductive Endocrinology, Ankara OBJECTIVE: The purpose of the present study is to compare the use of GnRH antagonist salvage versus coasting for the prevention of OHSS in patients undergoing IVF/ICSI cycles with long GnRH agonist protocol. STUDY DESIGN: Medical records of 91 patients (41 in coasting and 49 in GnRH antagonist group) identified as at high risk of developing OHSS were reviewed retrospectively. Groups were compared for occurrence of moderate and severe OHSS, serum estradiol on the day of HCG and IVF outcomes. RESULTS: There were no differences between the groups in terms of moderate and severe OHSS and clinical pregnancy rates. Serum estradiol levels were decreased significantly in GnRH antagonist group. Quality of the transferred embryos was better in the coasting group. CONCLUSION: Our results represent that both coasting and GnRH antagonist salvage are effective strategies to prevent OHSS in women undergoing long GnRH agonist IVF/ICSI cycles. https://gorm.com.tr/index.php/GORM/article/view/213OHSSCoastingGnRH antagonist |
| spellingShingle | Cavidan Gülerman Nafiye Yılmaz Ayla Sargın Oruç Nazlı Özkan Ayten Türkkanı Esma Sarıkaya Okan Yenicesu Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation Syndrome Gynecology Obstetrics & Reproductive Medicine OHSS Coasting GnRH antagonist |
| title | Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation Syndrome |
| title_full | Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation Syndrome |
| title_fullStr | Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation Syndrome |
| title_full_unstemmed | Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation Syndrome |
| title_short | Coasting Versus GnRH Antagonist Salvage for the Prevention of Ovarian Hyperstimulation Syndrome |
| title_sort | coasting versus gnrh antagonist salvage for the prevention of ovarian hyperstimulation syndrome |
| topic | OHSS Coasting GnRH antagonist |
| url | https://gorm.com.tr/index.php/GORM/article/view/213 |
| work_keys_str_mv | AT cavidangulerman coastingversusgnrhantagonistsalvageforthepreventionofovarianhyperstimulationsyndrome AT nafiyeyılmaz coastingversusgnrhantagonistsalvageforthepreventionofovarianhyperstimulationsyndrome AT aylasargınoruc coastingversusgnrhantagonistsalvageforthepreventionofovarianhyperstimulationsyndrome AT nazlıozkan coastingversusgnrhantagonistsalvageforthepreventionofovarianhyperstimulationsyndrome AT aytenturkkanı coastingversusgnrhantagonistsalvageforthepreventionofovarianhyperstimulationsyndrome AT esmasarıkaya coastingversusgnrhantagonistsalvageforthepreventionofovarianhyperstimulationsyndrome AT okanyenicesu coastingversusgnrhantagonistsalvageforthepreventionofovarianhyperstimulationsyndrome |