A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder

Abstract Previous studies investigating the correlation between mode of delivery and posttraumatic stress disorder (PTSD) have yielded inconsistent results. This study aims to investigate the association between mode of delivery and PTSD in a cohort of Chinese women with a high rate of cesarean sect...

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Main Authors: Baohong Xu, Yanfang Chen, Jiao Tang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-88717-7
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author Baohong Xu
Yanfang Chen
Jiao Tang
author_facet Baohong Xu
Yanfang Chen
Jiao Tang
author_sort Baohong Xu
collection DOAJ
description Abstract Previous studies investigating the correlation between mode of delivery and posttraumatic stress disorder (PTSD) have yielded inconsistent results. This study aims to investigate the association between mode of delivery and PTSD in a cohort of Chinese women with a high rate of cesarean section (CS). We conducted a prospective cohort study in China between October 2019 and June 2021. Women aged 20–45 years who give birth at The Seventh Hospital of the Southern Medical University during the study period were enrolled. PTSD was assessed by the Posttraumatic Stress Disorder Checklist-Civilian Version at 42 days postpartum. We examined the independent association between mode of birth and PTSD by log-binomial regression analysis. A total of 759/800 (94.88%) women completed questionnaire. The prevalence of postpartum PTSD was 12.12% in included women, 8.18% in women with vaginal delivery (VD), 17.55% in women with CS. After adjusting for confounding factors, it was found that women with elective CS (RR = 1.70, 95%CI, 1.03 to 2.87) and emergency CS (RR = 1.95, 95%CI, 1.08 to 3.83) had an increased risk of developing postpartum PTSD compared with women with VD. CS is identified as an independent risk factor for PTSD in a cohort of Chinese women with a high prevalence of CS.
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spelling doaj-art-cc22b0f9fe7d45b0ba77dd3079fa26ca2025-02-09T12:29:48ZengNature PortfolioScientific Reports2045-23222025-02-0115111010.1038/s41598-025-88717-7A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorderBaohong Xu0Yanfang Chen1Jiao Tang2Department of Emergency Medicine, Guangzhou Development District HospitalDepartment of General Surgery, The Third Affiliated Hospital, Guangzhou Medical UniversityDepartment of Nursing, The Seventh Affiliated Hospital of Southern Medical UniversityAbstract Previous studies investigating the correlation between mode of delivery and posttraumatic stress disorder (PTSD) have yielded inconsistent results. This study aims to investigate the association between mode of delivery and PTSD in a cohort of Chinese women with a high rate of cesarean section (CS). We conducted a prospective cohort study in China between October 2019 and June 2021. Women aged 20–45 years who give birth at The Seventh Hospital of the Southern Medical University during the study period were enrolled. PTSD was assessed by the Posttraumatic Stress Disorder Checklist-Civilian Version at 42 days postpartum. We examined the independent association between mode of birth and PTSD by log-binomial regression analysis. A total of 759/800 (94.88%) women completed questionnaire. The prevalence of postpartum PTSD was 12.12% in included women, 8.18% in women with vaginal delivery (VD), 17.55% in women with CS. After adjusting for confounding factors, it was found that women with elective CS (RR = 1.70, 95%CI, 1.03 to 2.87) and emergency CS (RR = 1.95, 95%CI, 1.08 to 3.83) had an increased risk of developing postpartum PTSD compared with women with VD. CS is identified as an independent risk factor for PTSD in a cohort of Chinese women with a high prevalence of CS.https://doi.org/10.1038/s41598-025-88717-7Mode of birthPosttraumatic stress disorderChinese womenCohort study
spellingShingle Baohong Xu
Yanfang Chen
Jiao Tang
A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder
Scientific Reports
Mode of birth
Posttraumatic stress disorder
Chinese women
Cohort study
title A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder
title_full A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder
title_fullStr A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder
title_full_unstemmed A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder
title_short A prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder
title_sort prospective cohort study of the association between mode of delivery and postpartum posttraumatic stress disorder
topic Mode of birth
Posttraumatic stress disorder
Chinese women
Cohort study
url https://doi.org/10.1038/s41598-025-88717-7
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