Advances in the study of apathy related to cerebral small vessel disease
Cerebral small vessel disease (CSVD) is a complex clinical-imaging pathological syndrome caused by small vessel lesions in the brain, which is characterized by aging-related, insidious onset and slow progression. Apathy is a key component of the common neuropsychiatric symptoms among CSVD patients,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1513574/full |
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| author | Shuo-han Bu Shuo-han Bu Xin-zhu Hu Zhe Su Li-tao Li Li-tao Li |
| author_facet | Shuo-han Bu Shuo-han Bu Xin-zhu Hu Zhe Su Li-tao Li Li-tao Li |
| author_sort | Shuo-han Bu |
| collection | DOAJ |
| description | Cerebral small vessel disease (CSVD) is a complex clinical-imaging pathological syndrome caused by small vessel lesions in the brain, which is characterized by aging-related, insidious onset and slow progression. Apathy is a key component of the common neuropsychiatric symptoms among CSVD patients, severely affecting their daily lives and social functioning. Moreover, there are fewer studies on CSVD-related apathy, and greater attention should be paid to this condition in clinical practice. This article describes the latest research advances in the concept, epidemiological features, pathogenesis, assessment and diagnosis, imaging and biomarkers, and treatment of CSVD-related apathy, aiming to serve as a reference for the clinical diagnosis and prevention of CSVD-related apathy. |
| format | Article |
| id | doaj-art-ccdec38041904fdbb1ca28008c4130db |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-ccdec38041904fdbb1ca28008c4130db2025-02-12T05:14:55ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-02-011610.3389/fneur.2025.15135741513574Advances in the study of apathy related to cerebral small vessel diseaseShuo-han Bu0Shuo-han Bu1Xin-zhu Hu2Zhe Su3Li-tao Li4Li-tao Li5Department of Neurology, Hebei North College, Zhangjiakou, ChinaDepartment of Neurology, Hebei General Hospital, Shijiazhuang, ChinaDepartment of Neurology, Hebei Medical University, Shijiazhuang, ChinaDepartment of Neurology, Hebei North College, Zhangjiakou, ChinaDepartment of Neurology, Hebei General Hospital, Shijiazhuang, ChinaHebei Provincial Key Laboratory of Cerebral Networks and Cognitive Disorders, Hebei General Hospital, Shijiazhuang, ChinaCerebral small vessel disease (CSVD) is a complex clinical-imaging pathological syndrome caused by small vessel lesions in the brain, which is characterized by aging-related, insidious onset and slow progression. Apathy is a key component of the common neuropsychiatric symptoms among CSVD patients, severely affecting their daily lives and social functioning. Moreover, there are fewer studies on CSVD-related apathy, and greater attention should be paid to this condition in clinical practice. This article describes the latest research advances in the concept, epidemiological features, pathogenesis, assessment and diagnosis, imaging and biomarkers, and treatment of CSVD-related apathy, aiming to serve as a reference for the clinical diagnosis and prevention of CSVD-related apathy.https://www.frontiersin.org/articles/10.3389/fneur.2025.1513574/fullcerebral small vessel diseaseapathypathogenesisbiomarkertreatment |
| spellingShingle | Shuo-han Bu Shuo-han Bu Xin-zhu Hu Zhe Su Li-tao Li Li-tao Li Advances in the study of apathy related to cerebral small vessel disease Frontiers in Neurology cerebral small vessel disease apathy pathogenesis biomarker treatment |
| title | Advances in the study of apathy related to cerebral small vessel disease |
| title_full | Advances in the study of apathy related to cerebral small vessel disease |
| title_fullStr | Advances in the study of apathy related to cerebral small vessel disease |
| title_full_unstemmed | Advances in the study of apathy related to cerebral small vessel disease |
| title_short | Advances in the study of apathy related to cerebral small vessel disease |
| title_sort | advances in the study of apathy related to cerebral small vessel disease |
| topic | cerebral small vessel disease apathy pathogenesis biomarker treatment |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1513574/full |
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