Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats
To determine the ameliorative effect of coconut water on haematobiochemical changes due to lead poisoning in wistar albino rats for six weeks, sixty rats were assigned to four groups. 0.10g/l of lead and 75ml coconut (cocus nucifera l.) water were given orally for six weeks. The mean values of re...
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Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)
2016-05-01
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| Series: | Journal of Applied Sciences and Environmental Management |
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| Online Access: | https://www.Ajol.Info/index.php/jasem/article/view/135144 |
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| author | Enagbonma Ben Jesuorsemwen Iyorah Imeda Ebikere Iyorah Imeda Ebikere Igiehon Nicholas Ozede Aimuanmwosa Frank Eghomwanre |
| author_facet | Enagbonma Ben Jesuorsemwen Iyorah Imeda Ebikere Iyorah Imeda Ebikere Igiehon Nicholas Ozede Aimuanmwosa Frank Eghomwanre |
| author_sort | Enagbonma Ben Jesuorsemwen |
| collection | DOAJ |
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To determine the ameliorative effect of coconut water on haematobiochemical changes due to lead poisoning in wistar albino rats for six weeks, sixty rats were assigned to four groups. 0.10g/l of lead and 75ml coconut (cocus nucifera l.) water were given orally for six weeks. The mean values of red blood cells, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, red blood cell distribution width and platelets (8.10±0.63(×106μl), 52.7±0.87(μm3), 17.9±0.56(pg), 34.73±0.65(g/dl), 17.90±0.67(%) and 670.00±42.22(×103μl) respectively) reduced in lead treated rats when compared with control mean values (8.41 ± 0.90(×106μl), 56.60 ± 1.55(μm3), 19.33 ± 0.82(pg), 34.93 ± 0.90(g/dl), 18.27 ± 0.73(%) and 818.33± 123.68(×103μl) respectively ) and these values increased in75ml coconut water only group and the group of 0.10g/l lead + 75ml coconut water except mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, and red blood cell distribution width of the 75ml coconut water only. The mean values of white blood cells, lymphocytes, total cholesterol, triglyceride, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol, low density lipoprotein-cholesterol/high density lipoproteincholesterol and total cholesterol/high density lipoprotein-cholesterol increased (12.23±0.57(×103μl), 79.83±3.87(%), 64.66±6.01(mg/dl), 89.00±7.94(mg/dl), 22.67±6.93(mg/dl), 21.00±4.58(mg/dl), 1.29±0.62 and 3.36±0.83 respectively ) in the lead group when compared with mean values of control group (5.83±0.74(×103μl), 69.07±10.57(%), 54.00±4.04(mg/dl), 97.33±11.34(mg/dl), 20.00±3.06(mg/dl), 17.00±6.51(mg/dl), 0.97±0.41 and 2.87±0.55 respectively) but the mean values decreased when compared with the mean values of group of 75ml coconut water only and group of 0.10g/l lead + 75ml coconut water, except the mean values of high density lipoprotein-cholesterol. These results indicate that coconut water could ameliorate effects of lead toxicity © JASEM
Keywords: Albino rats, Amelioration, Cocus nucifera L, Haematobiochemical, Lead toxicity.
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| format | Article |
| id | doaj-art-cdd051e2bcb24fa7bbd7c8cce9f8e539 |
| institution | Kabale University |
| issn | 2659-1502 2659-1499 |
| language | English |
| publishDate | 2016-05-01 |
| publisher | Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) |
| record_format | Article |
| series | Journal of Applied Sciences and Environmental Management |
| spelling | doaj-art-cdd051e2bcb24fa7bbd7c8cce9f8e5392025-02-08T19:51:43ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992016-05-01201Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino ratsEnagbonma Ben JesuorsemwenIyorah Imeda EbikereIyorah Imeda EbikereIgiehon Nicholas OzedeAimuanmwosa Frank Eghomwanre To determine the ameliorative effect of coconut water on haematobiochemical changes due to lead poisoning in wistar albino rats for six weeks, sixty rats were assigned to four groups. 0.10g/l of lead and 75ml coconut (cocus nucifera l.) water were given orally for six weeks. The mean values of red blood cells, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, red blood cell distribution width and platelets (8.10±0.63(×106μl), 52.7±0.87(μm3), 17.9±0.56(pg), 34.73±0.65(g/dl), 17.90±0.67(%) and 670.00±42.22(×103μl) respectively) reduced in lead treated rats when compared with control mean values (8.41 ± 0.90(×106μl), 56.60 ± 1.55(μm3), 19.33 ± 0.82(pg), 34.93 ± 0.90(g/dl), 18.27 ± 0.73(%) and 818.33± 123.68(×103μl) respectively ) and these values increased in75ml coconut water only group and the group of 0.10g/l lead + 75ml coconut water except mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, and red blood cell distribution width of the 75ml coconut water only. The mean values of white blood cells, lymphocytes, total cholesterol, triglyceride, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol, low density lipoprotein-cholesterol/high density lipoproteincholesterol and total cholesterol/high density lipoprotein-cholesterol increased (12.23±0.57(×103μl), 79.83±3.87(%), 64.66±6.01(mg/dl), 89.00±7.94(mg/dl), 22.67±6.93(mg/dl), 21.00±4.58(mg/dl), 1.29±0.62 and 3.36±0.83 respectively ) in the lead group when compared with mean values of control group (5.83±0.74(×103μl), 69.07±10.57(%), 54.00±4.04(mg/dl), 97.33±11.34(mg/dl), 20.00±3.06(mg/dl), 17.00±6.51(mg/dl), 0.97±0.41 and 2.87±0.55 respectively) but the mean values decreased when compared with the mean values of group of 75ml coconut water only and group of 0.10g/l lead + 75ml coconut water, except the mean values of high density lipoprotein-cholesterol. These results indicate that coconut water could ameliorate effects of lead toxicity © JASEM Keywords: Albino rats, Amelioration, Cocus nucifera L, Haematobiochemical, Lead toxicity. https://www.Ajol.Info/index.php/jasem/article/view/135144Albino ratsAmeliorationCocus nucifera LHaematobiochemicalLead toxicity. |
| spellingShingle | Enagbonma Ben Jesuorsemwen Iyorah Imeda Ebikere Iyorah Imeda Ebikere Igiehon Nicholas Ozede Aimuanmwosa Frank Eghomwanre Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats Journal of Applied Sciences and Environmental Management Albino rats Amelioration Cocus nucifera L Haematobiochemical Lead toxicity. |
| title | Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats |
| title_full | Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats |
| title_fullStr | Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats |
| title_full_unstemmed | Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats |
| title_short | Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats |
| title_sort | hematobiochemical changes of lead poisoning and amelioration with coconut i cocos nucifera i l water in wistar albino rats |
| topic | Albino rats Amelioration Cocus nucifera L Haematobiochemical Lead toxicity. |
| url | https://www.Ajol.Info/index.php/jasem/article/view/135144 |
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