Painful Todd’s: Post-ictal painful hemiparesis as an identifier of insular epilepsy

The insula can generate seizures which mimic frontal, temporal and parietal epilepsies making electroclinical localization difficult. We report the case of a twenty-one-year-old woman who presented with seizure semiology of a left-sided painful somatosensory aura, progressing to bilateral tonic post...

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Bibliographic Details
Main Authors: Julian Larkin, Tudor Munteanu, Emma Dolan, Daniel J. Costello, Kieron Sweeney, Ronan Kilbride, Peter Widdess-Walsh
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Epilepsy & Behavior Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589986425000073
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Summary:The insula can generate seizures which mimic frontal, temporal and parietal epilepsies making electroclinical localization difficult. We report the case of a twenty-one-year-old woman who presented with seizure semiology of a left-sided painful somatosensory aura, progressing to bilateral tonic posturing and complex manual automatisms. She described a painful sensation and weakness affecting her left side following the offset of a seizure, with the pain consistenly outlasting the weakness. This would last from hours to days depending on the severity and duration of the seizure. Stereo-electroencephalography (SEEG) demonstrated seizure onset in the limen of the right insula. Extra-operative stimulation of the insula reproduced the clinical symptoms. She underwent radiofrequency thermocoagulation (RFTC) which has resulted in a significant reduction in seizure frequency. This case report describes a lateralized painful Todd’s phenomenon as a feature of insular epilepsy confirmed by SEEG and extra-operative stimulation.
ISSN:2589-9864