In vivo regulation of the monocyte phenotype by Mycobacterium marinum and the ESX-1 type VII secretion system

Abstract Pathogenic mycobacteria require the conserved ESX-1 type VII secretion system to cause disease. In a murine Mycobacterium marinum infection model we previously demonstrated that infiltrating monocytes and neutrophils represent the major bacteria-harbouring cell populations in infected tissu...

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Bibliographic Details
Main Authors: Kristina Munke, Line Wulff, Julia Lienard, Fredric Carlsson, William W. Agace
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-88212-z
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